Stadium: Armfield Athletic Center Round: 1
| NCAAF | 2021/09/18 17:00 | Washington And Lee Generals v Guilford Quakers | L | 52-0 |
| NCAAF | 2019/09/21 17:00 | Washington And Lee Generals v Guilford Quakers | L | 52-14 |
| NCAAF | 2018/10/27 17:00 | Guilford Quakers v Washington And Lee Generals | W | 40-3 |
| NCAAF | 2022/10/01 17:00 | Randolph Macon Yellow Jackets v Guilford Quakers | L | 48-19 |
| NCAAF | 2022/09/17 17:00 | Guilford Quakers v Huntingdon Hawks | L | 7-47 |
| NCAAF | 2022/09/10 23:00 | Guilford Quakers v Methodist Monarchs | L | 16-49 |
| NCAAF | 2022/09/03 16:00 | Greensboro Pride v Guilford Quakers | W | 37-48 |
| NCAAF | 2021/11/13 19:00 | Bridgewater Eagles v Guilford Quakers | L | 43-0 |
| NCAAF | 2021/11/06 17:00 | Guilford Quakers v Emory And Henry Wasps | L | 13-66 |
| NCAAF | 2021/10/30 18:00 | Ferrum Panthers v Guilford Quakers | L | 57-35 |
| NCAAF | 2021/10/16 17:00 | Guilford Quakers v Randolph Macon Yellow Jackets | L | 0-58 |
| NCAAF | 2022/10/01 19:00 | Washington And Lee Generals v Averett Cougars | W | 31-0 |
| NCAAF | 2022/09/17 17:00 | Methodist Monarchs v Washington And Lee Generals | W | 14-37 |
| NCAAF | 2022/09/10 17:00 | Sewanee Tigers v Washington And Lee Generals | W | 0-44 |
| NCAAF | 2022/09/03 22:00 | Washington And Lee Generals v Christopher Newport Captains | L | 3-9 |
| NCAAF | 2021/11/20 17:00 | Mount Union v Washington And Lee Generals | L | 52-0 |
| NCAAF | 2021/11/13 18:00 | Shenandoah Hornets v Washington And Lee Generals | L | 14-6 |
| NCAAF | 2021/11/06 17:00 | Washington And Lee Generals v Ferrum Panthers | W | 28-24 |
| NCAAF | 2021/10/30 17:00 | Emory And Henry Wasps v Washington And Lee Generals | W | 28-30 |