Stadium: Pioneer Field Round: 1
| NCAAF | 2022/10/15 16:00 | Virginia Wise Highland Cavaliers v Tusculum Pioneers | W | 9-10 |
| NCAAF | 2022/10/08 17:30 | Tusculum Pioneers v Carson–Newman Eagles | W | 34-6 |
| NCAAF | 2022/09/29 21:00 | Barton Bulldogs v Tusculum Pioneers | W | 13-14 |
| NCAAF | 2022/09/24 20:00 | Catawba College v Tusculum Pioneers | W | 17-50 |
| NCAAF | 2022/09/17 22:00 | Tusculum Pioneers v Wingate Bulldogs | L | 10-27 |
| NCAAF | 2022/09/10 17:00 | Chowan Hawks v Tusculum Pioneers | W | 21-23 |
| NCAAF | 2022/09/01 22:00 | Tusculum Pioneers v St Augustines Falcons | W | 70-13 |
| NCAAF | 2021/11/13 18:30 | Tusculum Pioneers v Carson–Newman Eagles | W | 48-13 |
| NCAAF | 2022/10/15 17:30 | Mars Hill Lions v Emory And Henry Wasps | L | 49-14 |
| NCAAF | 2022/10/08 17:00 | Emory And Henry Wasps v Virginia Wise Highland Cavaliers | W | 34-14 |
| NCAAF | 2022/09/30 19:00 | Emory And Henry Wasps v Catawba College | W | 38-23 |
| NCAAF | 2022/09/24 22:00 | Wingate Bulldogs v Emory And Henry Wasps | W | 10-17 |
| NCAAF | 2022/09/17 17:00 | Emory And Henry Wasps v Newberry Wolves | L | 23-26 |
| NCAAF | 2022/09/10 22:00 | Bluefield College Rams v Emory And Henry Wasps | W | 33-41 |
| NCAAF | 2022/09/03 17:00 | Emory And Henry Wasps v Concord University Mountain Lions | L | 20-27 |
| NCAAF | 2021/11/13 18:00 | Emory And Henry Wasps v Ferrum Panthers | W | 41-23 |