Stadium: DiSanto Field Round: 1
| NCAAF | 2021/10/16 18:00 | Case Western Reserve Spartans v Bethany Bison | W | 53-0 |
| NCAAF | 2019/11/02 18:00 | Case Western Reserve Spartans v Bethany Bison | W | 35-14 |
| NCAAF | 2018/10/27 18:00 | Bethany Bison v Case Western Reserve Spartans | W | 3-34 |
| NCAAF | 2022/10/08 17:00 | Case Western Reserve Spartans v St Vincent Bearcats | W | 45-21 |
| NCAAF | 2022/10/01 18:00 | Grove City Wolverines v Case Western Reserve Spartans | L | 14-13 |
| NCAAF | 2022/09/24 23:00 | Geneva Golden Tornadoes v Case Western Reserve Spartans | W | 7-34 |
| NCAAF | 2022/09/17 23:00 | Case Western Reserve Spartans v Washington And Jefferson Presidents | W | 14-10 |
| NCAAF | 2022/09/10 17:00 | Waynesburg Yellow Jackets v Case Western Reserve Spartans | W | 31-45 |
| NCAAF | 2022/09/03 16:00 | Case Western Reserve Spartans v Johns Hopkins Blue Jays | L | 14-54 |
| NCAAF | 2021/11/13 18:00 | Carnegie Mellon Tartans v Case Western Reserve Spartans | L | 24-6 |
| NCAAF | 2021/11/06 17:00 | Case Western Reserve Spartans v Grove City Wolverines | W | 35-21 |
| NCAAF | 2022/10/15 17:00 | Bethany Bison v Waynesburg Yellow Jackets | L | 17-34 |
| NCAAF | 2022/10/08 17:00 | Bethany Bison v Grove City Wolverines | L | 7-55 |
| NCAAF | 2022/10/01 20:30 | Bethany Bison v Thiel Tomcats | L | 26-27 |
| NCAAF | 2022/09/24 22:00 | Washington And Jefferson Presidents v Bethany Bison | L | 50-7 |
| NCAAF | 2022/09/10 17:00 | Westminster Titans v Bethany Bison | L | 42-3 |
| NCAAF | 2022/09/03 17:00 | Bethany Bison v Hiram Terriers | W | 26-16 |
| NCAAF | 2021/11/13 18:00 | St Vincent Bearcats v Bethany Bison | L | 52-7 |
| NCAAF | 2021/11/06 17:00 | Waynesburg Yellow Jackets v Bethany Bison | L | 31-7 |