Stadium: Williams Stadium Round: 1
| NCAAF | 2021/09/25 17:30 | Muskingum Muskies v Wilmington Quakers | L | 62-14 |
| NCAAF | 2019/09/28 17:30 | Muskingum Muskies v Wilmington Quakers | L | 38-21 |
| NCAAF | 2018/09/22 18:00 | Wilmington Quakers v Muskingum Muskies | L | 24-31 |
| NCAAF | 2022/10/29 17:30 | Wilmington Quakers v Heidelberg Student Princes | L | 7-57 |
| NCAAF | 2022/10/22 17:30 | Mount Union v Wilmington Quakers | L | 63-3 |
| NCAAF | 2022/10/15 17:30 | Marietta Pioneers v Wilmington Quakers | L | 34-0 |
| NCAAF | 2022/10/01 17:30 | Wilmington Quakers v John Carroll Blue Streaks | L | 0-59 |
| NCAAF | 2022/09/24 17:30 | Capital Crusaders v Wilmington Quakers | W | 31-34 |
| NCAAF | 2022/09/17 18:00 | Wilmington Quakers v Otterbein Cardinals | W | 32-26 |
| NCAAF | 2022/09/10 17:30 | Wilmington Quakers v Baldwin Wallace Yellow Jackets | L | 12-13 |
| NCAAF | 2022/09/01 23:00 | Southern Virginia Knights v Wilmington Quakers | W | 27-52 |
| NCAAF | 2022/10/29 17:30 | Muskingum Muskies v John Carroll Blue Streaks | L | 14-49 |
| NCAAF | 2022/10/22 17:30 | Ohio Northern Polar Bears v Muskingum Muskies | W | 7-23 |
| NCAAF | 2022/10/15 17:30 | Baldwin Wallace Yellow Jackets v Muskingum Muskies | L | 35-21 |
| NCAAF | 2022/10/08 17:30 | Muskingum Muskies v Otterbein Cardinals | W | 41-35 |
| NCAAF | 2022/10/01 17:30 | Heidelberg Student Princes v Muskingum Muskies | L | 42-21 |
| NCAAF | 2022/09/24 17:30 | Muskingum Muskies v Mount Union | L | 0-59 |
| NCAAF | 2022/09/17 23:00 | Muskingum Muskies v Capital Crusaders | W | 37-7 |
| NCAAF | 2022/09/10 17:00 | Ferrum Panthers v Muskingum Muskies | W | 3-31 |