Stadium: Panther Stadium Round: 1
| NCAAF | 2021/10/02 17:00 | Kentucky Wesleyan v Ohio Dominican Panthers | W | 30-32 |
| NCAAF | 2019/10/19 18:00 | Kentucky Wesleyan v Ohio Dominican Panthers | W | 7-47 |
| NCAAF | 2018/11/03 16:00 | Ohio Dominican Panthers v Kentucky Wesleyan | W | 65-7 |
| NCAAF | 2022/10/15 23:00 | Ashland Eagles v Ohio Dominican Panthers | L | 14-7 |
| NCAAF | 2022/10/08 16:00 | Lake Erie v Ohio Dominican Panthers | W | 7-38 |
| NCAAF | 2022/10/01 17:00 | Ohio Dominican Panthers v Walsh U. Cavaliers | W | 21-0 |
| NCAAF | 2022/09/24 17:00 | Ohio Dominican Panthers v Indianapolis Greyhounds | L | 38-44 |
| NCAAF | 2022/09/17 17:00 | Ohio Dominican Panthers v William Jewell College Cardinals | W | 31-21 |
| NCAAF | 2022/09/10 17:00 | Tiffin Dragons v Ohio Dominican Panthers | L | 28-13 |
| NCAAF | 2022/09/03 16:00 | Ohio Dominican Panthers v Findlay Oilers | W | 28-14 |
| NCAAF | 2021/11/13 18:00 | Hillsdale Chargers v Ohio Dominican Panthers | L | 21-17 |
| NCAAF | 2022/10/15 21:00 | Kentucky Wesleyan v Findlay Oilers | L | 7-44 |
| NCAAF | 2022/10/08 18:00 | Quincy v Kentucky Wesleyan | L | 46-9 |
| NCAAF | 2022/10/01 23:00 | Kentucky Wesleyan v Hillsdale Chargers | W | 31-27 |
| NCAAF | 2022/09/24 18:00 | William Jewell College Cardinals v Kentucky Wesleyan | L | 24-17 |
| NCAAF | 2022/09/18 00:00 | Kentucky Wesleyan v Missouri S&t Miners | W | 11-6 |
| NCAAF | 2022/09/11 00:00 | Kentucky Wesleyan v Lake Erie | L | 21-26 |
| NCAAF | 2022/09/03 17:00 | Northwood Timberwolves v Kentucky Wesleyan | L | 55-13 |
| NCAAF | 2021/11/13 18:00 | Kentucky Wesleyan v Ashland Eagles | L | 0-17 |