Stadium: Memorial Stadium/Bob Cunningham Field Round: 1
| NCAAF | 2021/10/23 22:00 | Southwest Minnesota State Mustangs v Wayne State Wildcats | W | 16-38 |
| NCAAF | 2019/09/14 23:00 | Wayne State Wildcats v Southwest Minnesota State Mustangs | W | 19-13 |
| NCAAF | 2018/09/08 23:00 | Southwest Minnesota State Mustangs v Wayne State Wildcats | W | 14-23 |
| NCAAF | 2022/10/15 18:00 | Augustana Vikings v Wayne State Wildcats | L | 31-27 |
| NCAAF | 2022/10/08 18:00 | Wayne State Wildcats v Minnesota State Mankato Mavericks | W | 41-33 |
| NCAAF | 2022/10/01 18:00 | Winona State Warriors v Wayne State Wildcats | L | 38-14 |
| NCAAF | 2022/09/24 23:00 | Wayne State Wildcats v Concordia University Golden Bears | W | 48-21 |
| NCAAF | 2022/09/17 18:00 | Minot State Beavers v Wayne State Wildcats | W | 10-49 |
| NCAAF | 2022/09/10 23:00 | Wayne State Wildcats v Northern State Wolves | W | 13-6 |
| NCAAF | 2022/09/03 22:30 | University of Mary Marauders v Wayne State Wildcats | W | 28-33 |
| NCAAF | 2021/11/13 18:00 | Minnesota State University Moorhead Dragons v Wayne State Wildcats | W | 21-24 |
| NCAAF | 2022/10/15 18:00 | Southwest Minnesota State Mustangs v Winona State Warriors | L | 7-43 |
| NCAAF | 2022/10/08 18:00 | Sioux Falls Cougars v Southwest Minnesota State Mustangs | L | 35-14 |
| NCAAF | 2022/10/01 22:00 | Southwest Minnesota State Mustangs v Upper Iowa | W | 47-7 |
| NCAAF | 2022/09/24 22:00 | Southwest Minnesota State Mustangs v Minot State Beavers | W | 27-20 |
| NCAAF | 2022/09/17 19:00 | University of Mary Marauders v Southwest Minnesota State Mustangs | W | 28-31 |
| NCAAF | 2022/09/10 22:00 | Southwest Minnesota State Mustangs v Concordia University Golden Bears | W | 14-6 |
| NCAAF | 2022/09/01 23:00 | Minnesota Duluth Bulldogs v Southwest Minnesota State Mustangs | L | 31-21 |
| NCAAF | 2021/11/13 19:00 | Augustana Vikings v Southwest Minnesota State Mustangs | L | 55-0 |