Stadium: Robinson-Hale Stadium Round: 1
| NCAAF | 2022/10/22 21:00 | West Florida v Mississippi College Choctaws | L | 45-17 |
| NCAAF | 2021/10/30 19:00 | Mississippi College Choctaws v West Florida | L | 28-63 |
| NCAAF | 2019/09/28 22:00 | West Florida v Mississippi College Choctaws | L | 27-21 |
| NCAAF | 2018/09/23 00:00 | Mississippi College Choctaws v West Florida | L | 21-34 |
| NCAAF | 2022/11/05 19:00 | West Alabama Tigers v Mississippi College Choctaws | L | 38-16 |
| NCAAF | 2022/10/29 23:00 | Mississippi College Choctaws v Delta State | L | 38-52 |
| NCAAF | 2022/10/22 21:00 | West Florida v Mississippi College Choctaws | L | 45-17 |
| NCAAF | 2022/10/15 19:00 | Valdosta State v Mississippi College Choctaws | W | 40-49 |
| NCAAF | 2022/10/08 19:00 | Mississippi College Choctaws v Shorter | W | 35-21 |
| NCAAF | 2022/10/01 22:00 | West Georgia v Mississippi College Choctaws | W | 38-39 |
| NCAAF | 2022/09/25 00:00 | McNeese State v Mississippi College Choctaws | L | 32-17 |
| NCAAF | 2022/09/17 19:00 | Mississippi College Choctaws v North Greenville Crusaders | L | 19-41 |
| NCAAF | 2022/11/05 23:00 | Valdosta State v West Florida | W | 31-32 |
| NCAAF | 2022/10/29 21:00 | West Florida v West Alabama Tigers | W | 36-24 |
| NCAAF | 2022/10/22 21:00 | West Florida v Mississippi College Choctaws | W | 45-17 |
| NCAAF | 2022/10/15 16:00 | Shorter v West Florida | W | 26-50 |
| NCAAF | 2022/10/08 22:00 | West Georgia v West Florida | W | 28-42 |
| NCAAF | 2022/10/01 21:00 | West Florida v North Greenville Crusaders | W | 34-31 |
| NCAAF | 2022/09/24 23:00 | West Florida v Delta State | L | 42-45 |
| NCAAF | 2022/09/10 23:00 | Southwest Baptist University Bearcats v West Florida | W | 10-49 |