Stadium: Cook Stadium Round: 1
| NCAAF | 2021/10/02 17:30 | Defiance Yellow Jackets v Rose Hulman Engineers | W | 14-63 |
| NCAAF | 2019/11/02 17:30 | Rose Hulman Engineers v Defiance Yellow Jackets | W | 53-6 |
| NCAAF | 2018/10/27 17:30 | Defiance Yellow Jackets v Rose Hulman Engineers | W | 6-35 |
| NCAAF | 2022/10/22 17:30 | Rose Hulman Engineers v Franklin College Grizzlies | W | 49-0 |
| NCAAF | 2022/10/15 17:30 | Bluffton Beavers v Rose Hulman Engineers | W | 20-48 |
| NCAAF | 2022/10/08 18:00 | Rose Hulman Engineers v Manchester Spartans | W | 48-14 |
| NCAAF | 2022/10/01 17:30 | Anderson Ravens v Rose Hulman Engineers | W | 7-45 |
| NCAAF | 2022/09/17 16:00 | Rose Hulman Engineers v Albion Britons | L | 17-49 |
| NCAAF | 2022/09/10 23:00 | Rose Hulman Engineers v Trine Thunder | L | 23-24 |
| NCAAF | 2022/09/03 17:00 | Depauw Tigers v Rose Hulman Engineers | L | 17-14 |
| NCAAF | 2021/11/20 17:00 | Depauw Tigers v Rose Hulman Engineers | L | 26-21 |
| NCAAF | 2022/10/22 17:30 | Defiance Yellow Jackets v Anderson Ravens | W | 32-22 |
| NCAAF | 2022/10/15 17:30 | Franklin College Grizzlies v Defiance Yellow Jackets | L | 48-19 |
| NCAAF | 2022/10/08 17:30 | Mount St. Joseph Lions v Defiance Yellow Jackets | L | 55-35 |
| NCAAF | 2022/10/01 17:30 | Defiance Yellow Jackets v Hanover | L | 20-37 |
| NCAAF | 2022/09/24 16:00 | Alfred State Pioneers v Defiance Yellow Jackets | L | 42-33 |
| NCAAF | 2022/09/17 17:30 | Defiance Yellow Jackets v Kalamazoo Hornets | L | 23-42 |
| NCAAF | 2022/09/03 17:30 | Mount Union v Defiance Yellow Jackets | L | 65-0 |
| NCAAF | 2021/11/13 18:30 | Defiance Yellow Jackets v Bluffton Beavers | L | 12-30 |