Stadium: Faught Stadium Round: 1
| NCAAF | 2021/10/09 17:30 | Mount St. Joseph Lions v Franklin College Grizzlies | L | 28-14 |
| NCAAF | 2019/09/28 17:30 | Franklin College Grizzlies v Mount St. Joseph Lions | L | 27-50 |
| NCAAF | 2018/10/13 17:30 | Mount St. Joseph Lions v Franklin College Grizzlies | W | 34-42 |
| NCAAF | 2022/10/29 17:30 | Manchester Spartans v Franklin College Grizzlies | W | 6-24 |
| NCAAF | 2022/10/22 17:30 | Rose Hulman Engineers v Franklin College Grizzlies | L | 49-0 |
| NCAAF | 2022/10/15 17:30 | Franklin College Grizzlies v Defiance Yellow Jackets | W | 48-19 |
| NCAAF | 2022/10/08 17:30 | Franklin College Grizzlies v Anderson Ravens | W | 54-14 |
| NCAAF | 2022/10/01 17:30 | Bluffton Beavers v Franklin College Grizzlies | W | 27-37 |
| NCAAF | 2022/09/17 17:30 | Franklin College Grizzlies v Trine Thunder | L | 21-55 |
| NCAAF | 2022/09/10 18:00 | Aurora Spartans v Franklin College Grizzlies | L | 49-16 |
| NCAAF | 2022/09/03 18:00 | Olivet Comets v Franklin College Grizzlies | L | 35-31 |
| NCAAF | 2022/10/29 17:30 | Mount St. Joseph Lions v Bluffton Beavers | W | 70-21 |
| NCAAF | 2022/10/22 17:30 | Hanover v Mount St. Joseph Lions | W | 29-44 |
| NCAAF | 2022/10/15 17:30 | Anderson Ravens v Mount St. Joseph Lions | W | 3-59 |
| NCAAF | 2022/10/08 17:30 | Mount St. Joseph Lions v Defiance Yellow Jackets | W | 55-35 |
| NCAAF | 2022/10/01 17:30 | Manchester Spartans v Mount St. Joseph Lions | W | 20-55 |
| NCAAF | 2022/09/17 17:30 | Mount St. Joseph Lions v Hope Flying Dutchmen | W | 33-28 |
| NCAAF | 2022/09/10 16:00 | Alfred Saxons v Mount St. Joseph Lions | W | 37-43 |
| NCAAF | 2022/09/03 17:30 | Mount St. Joseph Lions v Baldwin Wallace Yellow Jackets | W | 31-28 |