Stadium: Spratt Memorial Stadium Round: 1
| NCAAF | 2021/11/13 17:00 | Blue Tigers v Missouri Western Griffons | W | 12-41 |
| NCAAF | 2019/11/16 18:00 | Blue Tigers v Missouri Western Griffons | W | 8-71 |
| NCAAF | 2022/11/05 18:00 | Central Missouri Mules v Missouri Western Griffons | L | 40-37 |
| NCAAF | 2022/10/29 18:00 | Missouri Western Griffons v Missouri Southern Lions | W | 31-27 |
| NCAAF | 2022/10/22 19:00 | Pittsburgh State Gorillas v Missouri Western Griffons | L | 28-16 |
| NCAAF | 2022/10/15 21:00 | Northeastern State Riverhawks v Missouri Western Griffons | W | 16-23 |
| NCAAF | 2022/10/08 21:00 | Missouri Western Griffons v Nebraska Kearney | L | 18-39 |
| NCAAF | 2022/10/01 18:30 | NW Missouri State v Missouri Western Griffons | L | 16-3 |
| NCAAF | 2022/09/24 23:00 | Missouri Western Griffons v Washburn Ichabods Football | L | 31-38 |
| NCAAF | 2022/09/17 18:00 | Emporia State v Missouri Western Griffons | L | 36-12 |
| NCAAF | 2022/11/05 19:00 | Blue Tigers v Emporia State | L | 24-35 |
| NCAAF | 2022/10/29 18:00 | Central Missouri Mules v Blue Tigers | L | 61-14 |
| NCAAF | 2022/10/22 19:00 | Blue Tigers v Nebraska Kearney | L | 17-66 |
| NCAAF | 2022/10/15 19:00 | Blue Tigers v Pittsburgh State Gorillas | L | 10-49 |
| NCAAF | 2022/10/08 19:00 | Missouri Southern Lions v Blue Tigers | L | 37-14 |
| NCAAF | 2022/10/01 19:00 | Blue Tigers v Central Oklahoma | L | 3-45 |
| NCAAF | 2022/09/24 19:00 | Northeastern State Riverhawks v Blue Tigers | L | 38-10 |
| NCAAF | 2022/09/17 23:00 | Blue Tigers v Fort Hays State University Tigers | L | 14-51 |