Stadium: Audrey J. Walton Stadium Round: 1
| NCAAF | 2021/10/02 19:00 | Northeastern State Riverhawks v Central Missouri Mules | W | 10-41 |
| NCAAF | 2019/09/13 00:00 | Northeastern State Riverhawks v Central Missouri Mules | W | 7-70 |
| NCAAF | 2018/09/07 00:00 | Central Missouri Mules v Northeastern State Riverhawks | W | 62-10 |
| NCAAF | 2022/09/24 18:00 | Nebraska Kearney v Central Missouri Mules | L | 38-6 |
| NCAAF | 2022/09/17 18:30 | NW Missouri State v Central Missouri Mules | L | 24-7 |
| NCAAF | 2022/09/09 00:00 | Central Missouri Mules v Washburn Ichabods Football | L | 32-40 |
| NCAAF | 2022/09/02 00:00 | Pittsburgh State Gorillas v Central Missouri Mules | L | 21-10 |
| NCAAF | 2021/11/13 19:00 | Central Missouri Mules v Central Oklahoma | W | 30-29 |
| NCAAF | 2021/11/06 18:00 | Missouri Western Griffons v Central Missouri Mules | L | 59-28 |
| NCAAF | 2021/10/30 19:00 | Blue Tigers v Central Missouri Mules | W | 35-77 |
| NCAAF | 2021/10/23 18:30 | Central Missouri Mules v Fort Hays State University Tigers | L | 17-21 |
| NCAAF | 2022/09/24 19:00 | Northeastern State Riverhawks v Blue Tigers | W | 38-10 |
| NCAAF | 2022/09/18 00:00 | Pittsburgh State Gorillas v Northeastern State Riverhawks | L | 49-14 |
| NCAAF | 2022/09/10 23:00 | Northeastern State Riverhawks v Missouri Southern Lions | L | 13-30 |
| NCAAF | 2022/09/02 00:00 | Emporia State v Northeastern State Riverhawks | L | 42-17 |
| NCAAF | 2021/11/13 18:00 | Nebraska Kearney v Northeastern State Riverhawks | L | 56-10 |
| NCAAF | 2021/10/30 18:00 | Washburn Ichabods Football v Northeastern State Riverhawks | L | 35-0 |
| NCAAF | 2021/10/23 18:00 | Northeastern State Riverhawks v NW Missouri State | L | 7-59 |
| NCAAF | 2021/10/16 21:00 | Missouri Western Griffons v Northeastern State Riverhawks | L | 57-24 |