Stadium: McPherson Memorial Stadium Round: 1
| NCAAF | 2021/10/23 18:00 | Edward Waters Tigers v Central State | L | 56-19 |
| NCAAF | 2019/10/05 17:00 | Central State v Edward Waters Tigers | W | 28-21 |
| NCAAF | 2022/10/15 18:00 | Tuskegee v Central State | L | 49-34 |
| NCAAF | 2022/10/08 17:00 | Central State v Fort Valley State | L | 17-32 |
| NCAAF | 2022/10/01 22:00 | Allen Yellow Jackets v Central State | W | 32-35 |
| NCAAF | 2022/09/24 17:00 | Central State v Miles Golden Bears | L | 14-34 |
| NCAAF | 2022/09/17 16:00 | Bluefield State v Central State | L | 27-23 |
| NCAAF | 2022/09/10 17:00 | Central State v Lincoln University | L | 21-26 |
| NCAAF | 2022/09/04 20:00 | Winston-Salem State v Central State | W | 21-41 |
| NCAAF | 2021/11/06 17:00 | Kentucky Thorobreds v Central State | L | 63-0 |
| NCAAF | 2022/10/15 17:00 | North Carolina A&T v Edward Waters Tigers | L | 45-7 |
| NCAAF | 2022/10/08 22:00 | Edward Waters Tigers v Albany State Golden Rams | L | 7-55 |
| NCAAF | 2022/10/02 18:00 | Edward Waters Tigers v Morehouse College Maroon Tigers | W | 49-20 |
| NCAAF | 2022/09/24 19:00 | Lane College Dragons v Edward Waters Tigers | L | 20-9 |
| NCAAF | 2022/09/10 22:00 | Edward Waters Tigers v Savannah State | L | 28-31 |
| NCAAF | 2022/09/03 20:00 | Edward Waters Tigers v Clark Atlanta University | L | 34-39 |
| NCAAF | 2022/08/27 20:00 | Florida Memorial University Lions v Edward Waters Tigers | L | 39-34 |
| NCAAF | 2021/11/06 21:00 | Savannah State v Edward Waters Tigers | L | 24-0 |