Stadium: Blackstock Stadium Round: 1
| NCAAF | 2021/11/13 18:07 | Wabash Little Giants v Depauw Tigers | L | 42-35 |
| NCAAF | 2019/11/16 18:00 | Depauw Tigers v Wabash Little Giants | W | 17-13 |
| NCAAF | 2018/11/10 18:07 | Wabash Little Giants v Depauw Tigers | L | 24-17 |
| NCAAF | 2022/11/05 17:00 | Depauw Tigers v Oberlin Yeomen | W | 72-0 |
| NCAAF | 2022/10/29 17:00 | Kenyon Lords v Depauw Tigers | W | 35-58 |
| NCAAF | 2022/10/22 17:00 | Ohio Wesleyan Battling Bishops v Depauw Tigers | W | 21-22 |
| NCAAF | 2022/10/08 17:00 | Depauw Tigers v Wittenberg Tigers | L | 7-30 |
| NCAAF | 2022/10/01 23:00 | Denison Big Red v Depauw Tigers | W | 13-17 |
| NCAAF | 2022/09/24 17:00 | Depauw Tigers v Wooster Scots | W | 59-0 |
| NCAAF | 2022/09/17 16:00 | Hiram Terriers v Depauw Tigers | W | 0-44 |
| NCAAF | 2022/09/10 22:00 | Anderson Ravens v Depauw Tigers | W | 0-55 |
| NCAAF | 2022/11/05 17:00 | Wabash Little Giants v Kenyon Lords | W | 49-25 |
| NCAAF | 2022/10/29 17:00 | Wabash Little Giants v Hiram Terriers | W | 59-23 |
| NCAAF | 2022/10/22 17:00 | Oberlin Yeomen v Wabash Little Giants | W | 20-66 |
| NCAAF | 2022/10/15 17:00 | Wabash Little Giants v Ohio Wesleyan Battling Bishops | W | 41-24 |
| NCAAF | 2022/10/01 17:00 | Wittenberg Tigers v Wabash Little Giants | W | 35-42 |
| NCAAF | 2022/09/24 18:00 | Wabash Little Giants v Denison Big Red | L | 42-45 |
| NCAAF | 2022/09/17 18:00 | Wooster Scots v Wabash Little Giants | W | 14-48 |
| NCAAF | 2022/09/10 17:00 | Wabash Little Giants v North Central Illinois | L | 12-56 |