Round: 1
| NCAAF | 2022/10/08 20:00 | Newberry Wolves v Barton Bulldogs | L | 42-21 |
| NCAAF | 2022/09/29 21:00 | Barton Bulldogs v Tusculum Pioneers | L | 13-14 |
| NCAAF | 2022/09/24 18:00 | Barton Bulldogs v Mars Hill Lions | L | 18-24 |
| NCAAF | 2022/09/17 17:00 | Virginia Wise Highland Cavaliers v Barton Bulldogs | W | 20-40 |
| NCAAF | 2022/09/10 23:00 | Davidson Wildcats v Barton Bulldogs | L | 37-17 |
| NCAAF | 2022/09/01 22:00 | Chowan Hawks v Barton Bulldogs | W | 3-17 |
| NCAAF | 2021/11/13 17:00 | Virginia Wise Highland Cavaliers v Barton Bulldogs | W | 24-36 |
| NCAAF | 2021/11/06 20:00 | Barton Bulldogs v Lenoir Rhyne Bears | L | 20-56 |
| NCAAF | 2022/10/08 17:00 | Lenoir Rhyne Bears v Limestone Saints | W | 51-30 |
| NCAAF | 2022/09/30 19:00 | Virginia Wise Highland Cavaliers v Lenoir Rhyne Bears | W | 10-42 |
| NCAAF | 2022/09/24 22:00 | Lenoir Rhyne Bears v Carson–Newman Eagles | W | 34-13 |
| NCAAF | 2022/09/17 20:00 | Erskine Flying Fleet v Lenoir Rhyne Bears | W | 20-42 |
| NCAAF | 2022/09/10 17:00 | Lenoir Rhyne Bears v Ferris State | L | 5-27 |
| NCAAF | 2022/09/03 22:00 | Lenoir Rhyne Bears v Virginia State Trojans | W | 38-19 |
| NCAAF | 2021/11/20 18:00 | Bowie State Bulldogs v Lenoir Rhyne Bears | L | 31-10 |
| NCAAF | 2021/11/13 18:00 | Lenoir Rhyne Bears v Catawba College | W | 56-3 |