Stadium: Edwards-Maurer Field Round: 1
| NCAAF | 2021/09/25 23:00 | Denison Big Red v Wittenberg Tigers | L | 21-16 |
| NCAAF | 2019/10/26 17:00 | Wittenberg Tigers v Denison Big Red | L | 13-24 |
| NCAAF | 2018/09/29 23:00 | Denison Big Red v Wittenberg Tigers | W | 66-68 |
| NCAAF | 2022/10/15 20:00 | Wittenberg Tigers v Oberlin Yeomen | W | 62-7 |
| NCAAF | 2022/10/08 17:00 | Depauw Tigers v Wittenberg Tigers | W | 7-30 |
| NCAAF | 2022/10/01 17:00 | Wittenberg Tigers v Wabash Little Giants | L | 35-42 |
| NCAAF | 2022/09/24 16:00 | Hiram Terriers v Wittenberg Tigers | W | 14-38 |
| NCAAF | 2022/09/17 17:00 | Kenyon Lords v Wittenberg Tigers | W | 28-51 |
| NCAAF | 2022/09/03 16:00 | Cortland Red Dragons v Wittenberg Tigers | L | 48-28 |
| NCAAF | 2021/11/13 18:00 | Wittenberg Tigers v Wooster Scots | W | 44-29 |
| NCAAF | 2021/11/06 17:00 | Wabash Little Giants v Wittenberg Tigers | W | 14-35 |
| NCAAF | 2022/10/15 19:00 | Denison Big Red v Hiram Terriers | W | 41-38 |
| NCAAF | 2022/10/08 18:00 | Ohio Wesleyan Battling Bishops v Denison Big Red | L | 41-7 |
| NCAAF | 2022/10/01 23:00 | Denison Big Red v Depauw Tigers | L | 13-17 |
| NCAAF | 2022/09/24 18:00 | Wabash Little Giants v Denison Big Red | W | 42-45 |
| NCAAF | 2022/09/17 17:00 | Denison Big Red v Oberlin Yeomen | W | 51-10 |
| NCAAF | 2022/09/10 16:00 | Hilbert Hawks v Denison Big Red | W | 0-63 |
| NCAAF | 2022/09/03 23:00 | Denison Big Red v Capital Crusaders | W | 48-31 |
| NCAAF | 2021/11/13 18:00 | Denison Big Red v Ohio Wesleyan Battling Bishops | L | 25-35 |