Stadium: Edwards-Maurer Field Round: 1
| NCAAF | 2022/11/05 17:00 | Wittenberg Tigers v Ohio Wesleyan Battling Bishops | L | 7-14 |
| NCAAF | 2022/10/29 17:30 | Wooster Scots v Wittenberg Tigers | L | 44-43 |
| NCAAF | 2022/10/22 16:00 | Wittenberg Tigers v Denison Big Red | L | 10-28 |
| NCAAF | 2022/10/15 20:00 | Wittenberg Tigers v Oberlin Yeomen | W | 62-7 |
| NCAAF | 2022/10/08 17:00 | Depauw Tigers v Wittenberg Tigers | W | 7-30 |
| NCAAF | 2022/10/01 17:00 | Wittenberg Tigers v Wabash Little Giants | L | 35-42 |
| NCAAF | 2022/09/24 16:00 | Hiram Terriers v Wittenberg Tigers | W | 14-38 |
| NCAAF | 2022/09/17 17:00 | Kenyon Lords v Wittenberg Tigers | W | 28-51 |
| NCAAF | 2022/11/05 17:00 | Hiram Terriers v Hilbert Hawks | L | 59-27 |
| NCAAF | 2022/10/22 17:00 | Wooster Scots v Hilbert Hawks | L | 49-7 |
| NCAAF | 2022/10/14 23:00 | Hilbert Hawks v Lincoln Oaklanders | L | 0-70 |
| NCAAF | 2022/09/24 17:00 | Curry Colonels v Hilbert Hawks | L | 49-9 |
| NCAAF | 2022/09/17 16:00 | Hilbert Hawks v Willamette Bearcats | L | 20-31 |
| NCAAF | 2022/09/10 16:00 | Hilbert Hawks v Denison Big Red | L | 0-63 |