Stadium: Edwin Fauver Stadium Round: 1
| NCAAF | 2021/10/30 17:00 | St Lawrence Saints v Rochester Yellowjackets | L | 34-10 |
| NCAAF | 2019/11/09 18:00 | St Lawrence Saints v Rochester Yellowjackets | L | 51-19 |
| NCAAF | 2018/10/06 17:00 | Rochester Yellowjackets v St Lawrence Saints | L | 24-38 |
| NCAAF | 2022/10/22 16:00 | Union Dutchmen v Rochester Yellowjackets | L | 27-7 |
| NCAAF | 2022/10/15 16:00 | Rochester Yellowjackets v Buffalo State Bengals | W | 12-6 |
| NCAAF | 2022/10/08 17:00 | Ithaca Bombers v Rochester Yellowjackets | L | 56-10 |
| NCAAF | 2022/10/01 17:00 | Rochester Yellowjackets v Rpi Engineers | L | 3-31 |
| NCAAF | 2022/09/17 16:00 | Rochester Yellowjackets v Brockport Golden Eagles | L | 3-23 |
| NCAAF | 2022/09/10 22:00 | Alfred State Pioneers v Rochester Yellowjackets | W | 17-30 |
| NCAAF | 2022/09/03 23:00 | Utica Pioneers v Rochester Yellowjackets | L | 43-28 |
| NCAAF | 2021/11/13 17:00 | Rochester Yellowjackets v Hobart Statesmen | L | 0-31 |
| NCAAF | 2022/10/22 17:00 | St Lawrence Saints v Hobart Statesmen | L | 10-31 |
| NCAAF | 2022/10/15 17:00 | Ithaca Bombers v St Lawrence Saints | L | 40-0 |
| NCAAF | 2022/10/08 17:00 | St Lawrence Saints v Union Dutchmen | L | 7-44 |
| NCAAF | 2022/09/24 16:00 | Castleton Spartans v St Lawrence Saints | W | 6-34 |
| NCAAF | 2022/09/16 23:00 | St Lawrence Saints v Morrisville State Mustangs | L | 15-17 |
| NCAAF | 2022/09/10 16:00 | Norwich Cadets v St Lawrence Saints | W | 19-30 |
| NCAAF | 2022/09/03 16:00 | St Lawrence Saints v Endicott Gulls | L | 0-27 |
| NCAAF | 2021/11/13 17:00 | Buffalo State Bengals v St Lawrence Saints | W | 6-41 |