| Colombia Regional League | 2022/06/16 12:19 | Molino Viejo v Medellin City FC | W | 3-1 |
| Colombia Regional League | 2022/08/11 12:00 | Molino Viejo v E.D.P IND. Medellin | D | 1-1 |
| Colombia Regional League | 2022/07/07 17:00 | Talento y Vida v Molino Viejo | W | 1-4 |
| Colombia Regional League | 2022/06/16 12:19 | Molino Viejo v Medellin City FC | W | 3-1 |
| Colombia Regional League | 2022/05/16 15:10 | Club Deportivo La Chalaca v Molino Viejo | L | 4-1 |
| Colombia Regional League | 2022/03/21 21:32 | Molino Viejo v Envigado FC Reserves | D | 0-0 |
| Colombia Regional League | 2022/03/09 16:42 | Sol de Oriente v Molino Viejo | L | 1-0 |
| Colombia Regional League | 2022/02/28 16:29 | Molino Viejo v FC Leones Reserves | W | 2-0 |
| Colombia Regional League | 2021/12/04 19:20 | Envigado FC Reserves v Molino Viejo | L | 1-0 |
| Colombia Regional League | 2022/09/07 17:00 | Sol de Oriente v Medellin City FC | L | 2-1 |
| Colombia Regional League | 2022/08/30 15:00 | Medellin City FC v FC Leones Reserves | W | 4-0 |
| Colombia Regional League | 2022/08/15 15:13 | Real Santuario v Medellin City FC | L | 4-0 |
| Colombia Regional League | 2022/08/02 19:17 | Medellin City FC v Universidad de Antioquia | L | 0-1 |
| Colombia Regional League | 2022/07/11 16:00 | CD Gallegol v Medellin City FC | W | 2-4 |
| Colombia Regional League | 2022/07/05 15:23 | Medellin City FC v E.D.P IND. Medellin | W | 4-1 |
| Colombia Regional League | 2022/06/16 12:19 | Molino Viejo v Medellin City FC | L | 3-1 |
| Colombia Regional League | 2022/05/27 15:00 | Club Deportivo La Chalaca v Medellin City FC | L | 4-1 |