| France National 2 | 2022/08/20 16:00 | Frejus v Lyon II | L | 2-0 |
| France National 2 | 2022/05/28 16:00 | Monaco II v Lyon II | L | 4-1 |
| France National 2 | 2022/05/14 16:00 | Hyeres FC v Lyon II | D | 1-1 |
| France National 2 | 2022/04/29 18:00 | Lyon II v Louhans-Cuiseaux | W | 2-0 |
| France National 2 | 2022/04/23 16:00 | Grasse v Lyon II | L | 2-1 |
| France National 2 | 2022/04/16 16:00 | Sporting Club Toulon v Lyon II | L | 2-1 |
| France National 2 | 2022/04/09 14:00 | Lyon II v Marignane | W | 3-1 |
| France National 2 | 2022/03/26 17:00 | Marseille II v Lyon II | W | 0-2 |
| France National 2 | 2022/09/10 17:00 | Olympique d'Ales v Auxerre II | W | 1-5 |
| France National 2 | 2022/08/27 16:00 | Grasse v Auxerre II | D | 0-0 |
| France National 2 | 2022/08/20 16:00 | Auxerre II v Hyeres FC | W | 2-0 |
| France National 2 | 2022/05/14 16:00 | Schiltigheim v Auxerre II | L | 2-0 |
| France National 2 | 2022/04/30 16:00 | Auxerre II v Metz II | D | 2-2 |
| France National 2 | 2022/04/23 16:00 | US Lusitanos Saint-Maur v Auxerre II | W | 0-1 |
| France National 2 | 2022/04/16 16:00 | Auxerre II v FC Fleury 91 | L | 1-3 |
| France National 2 | 2022/03/26 16:00 | Auxerre II v St Quentin | W | 1-0 |