| Guatemala Reserve League | 2022/04/30 21:00 | CSD Municipal Reserves v Deportivo Iztapa Reserves | W | 3-4 |
| Guatemala Reserve League | 2022/08/31 14:00 | Malacateco Reserves v Deportivo Iztapa Reserves | L | 3-0 |
| Guatemala Reserve League | 2022/08/28 21:00 | Deportivo Iztapa Reserves v Antigua GFC Reserves | L | 0-3 |
| Guatemala Reserve League | 2022/08/10 21:15 | Deportivo Iztapa Reserves v Coban Imperial Reserves | L | 1-5 |
| Guatemala Reserve League | 2022/05/04 20:00 | Deportivo Iztapa Reserves v CD Achuapa Reserves | L | 2-3 |
| Guatemala Reserve League | 2022/04/30 21:00 | CSD Municipal Reserves v Deportivo Iztapa Reserves | W | 3-4 |
| Guatemala Reserve League | 2022/04/24 21:00 | Deportivo Iztapa Reserves v Antigua GFC Reserves | W | 5-2 |
| Guatemala Reserve League | 2022/04/20 20:00 | Deportivo Iztapa Reserves v Coban Imperial Reserves | D | 2-2 |
| Guatemala Reserve League | 2022/04/17 18:00 | Nueva Concepcion Reserves v Deportivo Iztapa Reserves | W | 0-3 |
| Guatemala Reserve League | 2022/09/24 16:00 | Coban Imperial Reserves v CSD Municipal Reserves | W | 0-2 |
| Guatemala Reserve League | 2022/08/31 21:00 | Deportivo Mixco Reserves v CSD Municipal Reserves | W | 0-1 |
| Guatemala Reserve League | 2022/08/20 21:00 | CSD Comunicaciones Reserves v CSD Municipal Reserves | D | 0-0 |
| Guatemala Reserve League | 2022/08/10 17:00 | Antigua GFC Reserves v CSD Municipal Reserves | W | 0-2 |
| Guatemala Reserve League | 2022/07/23 21:00 | CSD Municipal Reserves v Coban Imperial Reserves | W | 3-0 |
| Guatemala Reserve League | 2022/05/04 18:30 | CSD Municipal Reserves v Antigua GFC Reserves | W | 7-0 |
| Guatemala Reserve League | 2022/04/30 21:00 | CSD Municipal Reserves v Deportivo Iztapa Reserves | L | 3-4 |
| Guatemala Reserve League | 2022/04/16 21:00 | Xelaju Reserves v CSD Municipal Reserves | W | 0-3 |