| Guatemala Liga Nacional Women | 2022/09/25 17:00 | Club Deportivo Xela Women v CSD Concepcion Women | W | 4-0 |
| Guatemala Liga Nacional Women | 2022/09/18 16:00 | CSD Municipal Women v Club Deportivo Xela Women | D | 0-0 |
| Guatemala Liga Nacional Women | 2022/09/11 19:00 | Club Deportivo Xela Women v Deportivo Mixco Women | W | 5-1 |
| Guatemala Liga Nacional Women | 2022/08/28 19:00 | Club Deportivo Xela Women v Suchitepequez Women | W | 1-0 |
| Guatemala Liga Nacional Women | 2022/06/19 17:00 | Suchitepequez Women v Club Deportivo Xela Women | D | 0-0 |
| Guatemala Liga Nacional Women | 2022/06/05 16:30 | UNIFUT Antigua Women v Club Deportivo Xela Women | D | 1-1 |
| Guatemala Liga Nacional Women | 2022/05/22 19:00 | Club Deportivo Xela Women v FC Cremas Women | W | 3-1 |
| Guatemala Liga Nacional Women | 2022/04/24 19:00 | Club Deportivo Xela Women v Xinabajul Women | W | 4-0 |
| Guatemala Liga Nacional Women | 2022/09/18 16:00 | FC Cremas Women v Antigua GFC Women | L | 3-1 |
| Guatemala Liga Nacional Women | 2022/08/28 16:00 | Antigua GFC Women v CSD Municipal Women | L | 0-4 |
| Guatemala Liga Nacional Women | 2022/06/05 16:00 | Antigua GFC Women v FC Moralense Women | L | 0-1 |
| Guatemala Liga Nacional Women | 2022/05/29 16:00 | Antigua GFC Women v Deportivo Mixco Women | W | 3-1 |
| Guatemala Liga Nacional Women | 2022/05/22 21:00 | Deportivo Mixco Women v Antigua GFC Women | W | 1-3 |
| Guatemala Liga Nacional Women | 2022/05/15 16:00 | Antigua GFC Women v FCF El Estor Women | W | 2-0 |
| Guatemala Liga Nacional Women | 2022/05/08 21:00 | FCF El Estor Women v Antigua GFC Women | W | 0-1 |
| Guatemala Liga Nacional Women | 2022/04/10 17:00 | K’iche FC Women v Antigua GFC Women | W | 0-1 |