[3] TOR Maple Leafs 3-5 BUF Sabres [16] 2018-03-06 00:30
Stadium: KeyBank Center Round: 1
Home Manager: Phil Housley Away Manager: Mike Babcock
Head to Head
| NHL Pre-Season | 2017/09/23 23:00 | BUF Sabres v TOR Maple Leafs | W | 1-3 |
| NHL Pre-Season | 2017/09/22 23:30 | BUF Sabres v TOR Maple Leafs | W | 0-3 |
| NHL | 2017/04/03 23:00 | TOR Maple Leafs v BUF Sabres | W | 4-2 |
| NHL | 2017/03/25 23:00 | TOR Maple Leafs v BUF Sabres | L | 2-5 |
| NHL | 2017/02/12 00:00 | BUF Sabres v TOR Maple Leafs | L | 3-1 |
| NHL | 2017/01/18 00:30 | BUF Sabres v TOR Maple Leafs | W | 3-4 |
| NHL | 2016/11/03 23:00 | TOR Maple Leafs v BUF Sabres | W | 2-1 |
Home History
| NHL | 2018/03/04 01:00 | TOR Maple Leafs v WAS Capitals | L | 2-5 |
| NHL | 2018/02/28 00:30 | TOR Maple Leafs v FLA Panthers | L | 2-3 |
| NHL | 2018/02/27 00:30 | TOR Maple Leafs v TB Lightning | L | 3-4 |
| NHL | 2018/02/25 00:00 | BOS Bruins v TOR Maple Leafs | W | 3-4 |
| NHL | 2018/02/23 00:00 | NY Islanders v TOR Maple Leafs | W | 3-4 |
| NHL | 2018/02/21 00:00 | FLA Panthers v TOR Maple Leafs | W | 0-1 |
| NHL | 2018/02/19 00:00 | TOR Maple Leafs v DET Red Wings | W | 3-2 |
| NHL | 2018/02/18 00:00 | TOR Maple Leafs v PIT Penguins | L | 3-5 |
Away History
| NHL | 2018/03/03 00:30 | BUF Sabres v FLA Panthers | L | 1-4 |
| NHL | 2018/03/01 00:00 | BUF Sabres v TB Lightning | W | 2-1 |
| NHL | 2018/02/25 22:00 | BOS Bruins v BUF Sabres | W | 1-4 |
| NHL | 2018/02/25 00:00 | BUF Sabres v WAS Capitals | L | 1-5 |
| NHL | 2018/02/23 00:30 | BUF Sabres v DET Red Wings | W | 3-2 |
| NHL | 2018/02/19 20:00 | WAS Capitals v BUF Sabres | L | 3-2 |
| NHL | 2018/02/17 18:00 | LA Kings v BUF Sabres | L | 4-2 |
| NHL | 2018/02/16 00:30 | BUF Sabres v OTT Senators | L | 2-3 |