| Colombia Regional League | 2022/10/04 17:00 | Medellin City FC v Politecnico J.I.C. | L | 3-0 |
| Colombia Regional League | 2022/09/20 17:00 | Total Soccer FC v Politecnico J.I.C. | D | 0-0 |
| Colombia Regional League | 2022/09/06 17:00 | Politecnico J.I.C. v Club Deportivo La Chalaca | W | 3-1 |
| Colombia Regional League | 2022/08/30 00:00 | Real San Jeronimo v Politecnico J.I.C. | L | 2-1 |
| Colombia Regional League | 2022/07/20 21:27 | Estudiantes de Medellin v Politecnico J.I.C. | L | 1-0 |
| Colombia Regional League | 2022/06/15 17:18 | Sol de Oriente v Politecnico J.I.C. | D | 0-0 |
| Colombia Regional League | 2022/05/24 17:12 | Real Santuario v Politecnico J.I.C. | L | 3-0 |
| Colombia Regional League | 2022/05/03 17:09 | Politecnico J.I.C. v Independiente Sabaneta | W | 3-1 |
| Colombia Regional League | 2022/10/24 15:00 | Deportivo Alexis Garcia v Medellin City FC | L | 0-3 |
| Colombia Regional League | 2022/09/17 19:00 | Deportivo Alexis Garcia v Talento y Vida | W | 2-0 |
| Colombia Regional League | 2022/09/03 18:52 | Deportivo Alexis Garcia v CD Gallegol | D | 1-1 |
| Colombia Regional League | 2022/08/29 16:21 | E.D.P IND. Medellin v Deportivo Alexis Garcia | D | 1-1 |
| Colombia Regional League | 2022/07/02 19:15 | Club Deportivo La Chalaca v Deportivo Alexis Garcia | W | 0-4 |
| Colombia Regional League | 2022/06/11 21:16 | Deportivo Alexis Garcia v Real San Jeronimo | W | 1-0 |
| Colombia Regional League | 2022/03/27 13:12 | Real Santuario v Deportivo Alexis Garcia | W | 0-2 |
| Colombia Regional League | 2022/03/21 17:18 | Deportivo Alexis Garcia v Universidad de Antioquia | W | 3-0 |