[4] Libertad Asuncion 4-2 Guairena FC [6] 2022-11-06 20:00
Stadium: Estadio Dr. Nicolás Léoz Round: 21
Referee: Juan Lopez Home Manager: Daniel Garnero Away Manager: Victor Hugo Cabrera
Head to Head
| Paraguay Division Profesional | 2022/09/10 20:45 | Guairena FC v Libertad Asuncion | L | 4-0 |
| Paraguay Division Profesional | 2022/06/17 23:15 | Libertad Asuncion v Guairena FC | W | 2-0 |
| Paraguay Division Profesional | 2022/04/02 22:00 | Guairena FC v Libertad Asuncion | W | 2-3 |
| Paraguay Division Profesional | 2021/09/27 00:15 | Guairena FC v Libertad Asuncion | L | 2-1 |
| Paraguay Division Profesional | 2021/07/18 23:30 | Libertad Asuncion v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2021/04/12 00:30 | Libertad Asuncion v Guairena FC | W | 2-1 |
| Paraguay Division Profesional | 2021/02/24 22:00 | Guairena FC v Libertad Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2020/10/17 23:15 | Guairena FC v Libertad Asuncion | W | 0-3 |
Home History
| Paraguay Division Profesional | 2022/10/31 23:00 | Libertad Asuncion v Cerro Porteno | D | 0-0 |
| Paraguay Division Profesional | 2022/10/27 20:00 | Guarani Asuncion v Libertad Asuncion | W | 1-2 |
| Paraguay Division Profesional | 2022/10/23 22:30 | Libertad Asuncion v Nacional Asuncion | L | 0-1 |
| Paraguay Division Profesional | 2022/10/17 22:00 | Sol de America v Libertad Asuncion | D | 1-1 |
| Paraguay Division Profesional | 2022/10/12 22:30 | Olimpia Asuncion v Libertad Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2022/10/09 22:30 | Libertad Asuncion v 12 de Octubre | D | 2-2 |
| Paraguay Division Profesional | 2022/10/06 20:30 | Resistencia FC v Libertad Asuncion | L | 1-0 |
| Paraguay Division Profesional | 2022/10/02 22:30 | Libertad Asuncion v General Caballero JLM | W | 1-0 |
Away History
| Paraguay Division Profesional | 2022/10/30 20:00 | Guairena FC v Guarani Asuncion | W | 1-0 |
| Paraguay Division Profesional | 2022/10/27 20:00 | Nacional Asuncion v Guairena FC | L | 3-0 |
| Paraguay Division Profesional | 2022/10/21 20:00 | Guairena FC v Sol de America | D | 0-0 |
| Paraguay Division Profesional | 2022/10/14 22:00 | 12 de Octubre v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2022/10/10 20:00 | Guairena FC v Resistencia FC | W | 3-2 |
| Paraguay Division Profesional | 2022/10/05 20:30 | General Caballero JLM v Guairena FC | D | 0-0 |
| Paraguay Division Profesional | 2022/10/02 20:00 | Guairena FC v Olimpia Asuncion | L | 0-1 |
| Paraguay Cup | 2022/09/27 20:30 | Guairena FC v Sportivo Ameliano | L | 0-2 |