Stadium: Hart Recreation Center
Home Manager: Brett Nelson Away Manager: Carmen Maciariello
| NCAAB | 2021/12/11 19:00 | Siena v Holy Cross | W | 72-59 |
| NCAAB | 2019/12/29 19:00 | Holy Cross v Siena | W | 62-74 |
| NCAAB | 2018/12/22 17:05 | Siena v Holy Cross | L | 57-60 |
| NCAAB | 2018/11/18 16:00 | Holy Cross v Siena | L | 57-45 |
| NCAAB | 2017/12/23 00:00 | Siena v Holy Cross | W | 71-65 |
| NCAAB | 2008/12/30 12:00 | Holy Cross v Siena | W | 71-83 |
| NCAAB | 2007/12/22 12:00 | Siena v Holy Cross | W | 84-77 |
| NCAAB | 2006/11/18 12:00 | Holy Cross v Siena | L | 65-57 |
| NCAAB | 2022/03/11 00:00 | Quinnipiac v Siena | L | 77-71 |
| NCAAB | 2022/03/05 21:00 | Siena v Canisius | L | 64-67 |
| NCAAB | 2022/03/04 00:00 | Siena v Niagara | L | 52-74 |
| NCAAB | 2022/02/27 19:00 | Monmouth v Siena | W | 59-70 |
| NCAAB | 2022/02/25 00:00 | Siena v Quinnipiac | W | 78-71 |
| NCAAB | 2022/02/23 00:00 | Siena v Monmouth | L | 59-71 |
| NCAAB | 2022/02/20 19:00 | St. Peter's v Siena | W | 70-84 |
| NCAAB | 2022/02/19 00:00 | Marist v Siena | L | 62-53 |
| NCAAB | 2022/03/02 00:00 | American v Holy Cross | L | 69-63 |
| NCAAB | 2022/02/26 19:00 | Army v Holy Cross | L | 66-58 |
| NCAAB | 2022/02/24 00:00 | Colgate v Holy Cross | L | 78-71 |
| NCAAB | 2022/02/22 00:00 | Holy Cross v Lafayette | L | 61-84 |
| NCAAB | 2022/02/19 17:00 | Holy Cross v Navy | W | 55-50 |
| NCAAB | 2022/02/17 00:00 | Boston U v Holy Cross | L | 78-65 |
| NCAAB | 2022/02/15 00:00 | American v Holy Cross | L | 60-54 |
| NCAAB | 2022/02/12 19:00 | Holy Cross v Bucknell | W | 78-72 |