Stadium: Watsco Center
Home Manager: Jim Larranaga Away Manager: Mike Jordan
| NCAAB | 2022/03/02 00:00 | Bucknell v Lafayette | L | 82-81 |
| NCAAB | 2022/02/26 19:00 | Lehigh v Lafayette | L | 78-58 |
| NCAAB | 2022/02/24 00:00 | Lafayette v Boston U | L | 60-76 |
| NCAAB | 2022/02/22 00:00 | Holy Cross v Lafayette | W | 61-84 |
| NCAAB | 2022/02/19 21:00 | Lafayette v Bucknell | L | 89-92 |
| NCAAB | 2022/02/17 00:00 | Loyola Maryland v Lafayette | W | 68-77 |
| NCAAB | 2022/02/14 23:00 | Lafayette v Colgate | L | 61-69 |
| NCAAB | 2022/02/12 17:00 | Lafayette v Lehigh | W | 73-69 |
| NCAAB | 2022/03/27 18:20 | Miami Florida v Kansas | L | 50-76 |
| NCAAB | 2022/03/26 01:59 | Iowa State v Miami Florida | W | 56-70 |
| NCAAB | 2022/03/20 23:45 | Miami Florida v Auburn | W | 79-61 |
| NCAAB | 2022/03/18 19:10 | Miami Florida v USC Trojans | W | 68-66 |
| NCAAB | 2022/03/12 00:00 | Miami Florida v Duke | L | 76-80 |
| NCAAB | 2022/03/10 19:30 | Boston College v Miami Florida | W | 69-71 |
| NCAAB | 2022/03/05 18:00 | Miami Florida v Syracuse | W | 75-72 |
| NCAAB | 2022/03/03 02:00 | Miami Florida v Boston College | W | 81-70 |