Stadium: Willett Hall
Home Manager: Brian Barone Away Manager: Tobin Anderson
| NCAAB | 2022/11/16 01:00 | SIU Edwardsville v Missouri | L | 80-105 |
| NCAAB | 2022/11/12 18:00 | SIU Edwardsville v IPFW | L | 76-81 |
| NCAAB | 2022/11/08 01:00 | Harris Stowe v SIU Edwardsville | W | 57-85 |
| NCAAB | 2022/03/03 00:30 | SIU Edwardsville v Tennessee State | L | 62-77 |
| NCAAB | 2022/02/26 21:30 | Morehead State v SIU Edwardsville | W | 70-77 |
| NCAAB | 2022/02/25 01:30 | Austin Peay v SIU Edwardsville | L | 68-64 |
| NCAAB | 2022/02/22 01:00 | Eastern Illinois v SIU Edwardsville | W | 52-66 |
| NCAAB | 2022/02/19 22:00 | SIU Edwardsville v Belmont | L | 62-73 |
| NCAAB | 2022/11/13 22:00 | Manhattan v Fairleigh Dickinson | W | 74-77 |
| NCAAB | 2022/11/10 00:00 | Mercy v Fairleigh Dickinson | W | 66-106 |
| NCAAB | 2022/11/08 01:00 | Fairleigh Dickinson v Loyola Chicago | L | 82-88 |
| NCAAB | 2022/03/01 00:00 | Central Connecticut v Fairleigh Dickinson | L | 67-66 |
| NCAAB | 2022/02/26 19:00 | Fairleigh Dickinson v LIU Brooklyn | L | 77-84 |
| NCAAB | 2022/02/24 23:00 | Wagner v Fairleigh Dickinson | W | 86-88 |
| NCAAB | 2022/02/19 18:00 | Fairleigh Dickinson v Bryant | L | 93-105 |
| NCAAB | 2022/02/18 00:00 | Fairleigh Dickinson v Merrimack | L | 44-64 |