Stadium: Screaming Eagles Arena
Home Manager: Stan Gouard Away Manager: Bryan Mullins
| NCAAB | 2022/11/11 01:00 | Southern Illinois v Oklahoma State | W | 61-60 |
| NCAAB | 2022/11/08 01:00 | Arkansas LR v Southern Illinois | W | 63-94 |
| NCAAB | 2022/03/05 02:30 | Southern Illinois v Drake | L | 52-65 |
| NCAAB | 2022/02/26 21:00 | Southern Illinois v Drake | L | 60-62 |
| NCAAB | 2022/02/24 01:00 | Illinois St v Southern Illinois | W | 69-90 |
| NCAAB | 2022/02/19 18:00 | Southern Illinois v Indiana State | W | 76-72 |
| NCAAB | 2022/02/16 01:00 | Bradley v Southern Illinois | W | 57-65 |
| NCAAB | 2022/02/13 01:00 | Evansville v Southern Illinois | W | 62-69 |
| NCAAB | 2022/11/08 01:00 | Southern Indiana v Missouri | L | 91-97 |
| NCAAB | 2021/11/23 00:00 | Cedarville v Southern Indiana | L | 101-88 |
| NCAAB | 2021/02/15 21:00 | Southern Indiana v Truman State | L | 72-75 |
| NCAAB | 2021/02/13 20:00 | Southern Indiana v Drury | W | 91-90 |
| NCAAB | 2021/02/10 23:00 | Southern Indiana v Quincy University | W | 86-71 |
| NCAAB | 2021/02/06 20:00 | Rockhurst v Southern Indiana | W | 57-67 |
| NCAAB | 2021/01/23 20:30 | Illinois Springfield v Southern Indiana | W | 69-88 |
| NCAAB | 2021/01/22 00:30 | Lewis v Southern Indiana | W | 65-74 |