Stadium: Northwest Florida State College Arena
Home Manager: Tavaras Hardy Away Manager: Sean Woods
| NCAAB | 2022/11/19 02:00 | Southern v California | W | 74-66 |
| NCAAB | 2022/11/17 01:30 | Southern v Saint Mary's CA | L | 54-72 |
| NCAAB | 2022/11/12 02:00 | Southern v Arizona | L | 78-95 |
| NCAAB | 2022/11/08 03:15 | Southern v UNLV | L | 56-66 |
| NCAAB | 2022/03/10 20:00 | Grambling State v Southern | L | 60-58 |
| NCAAB | 2022/03/05 22:00 | Southern v Alabama A&M | W | 50-49 |
| NCAAB | 2022/03/04 02:00 | Southern v Alabama State | L | 67-77 |
| NCAAB | 2022/03/01 02:00 | Florida A&M v Southern | W | 49-58 |
| NCAAB | 2022/11/22 00:00 | Loyola Maryland v Clemson | L | 41-72 |
| NCAAB | 2022/11/18 00:00 | Washington University v Loyola Maryland | W | 53-81 |
| NCAAB | 2022/11/13 22:00 | Brown v Loyola Maryland | W | 70-75 |
| NCAAB | 2022/11/11 00:00 | Loyola Maryland v Penn State | L | 65-90 |
| NCAAB | 2022/11/08 00:45 | Loyola Maryland v DePaul | L | 66-72 |
| NCAAB | 2022/03/04 00:00 | Loyola Maryland v Boston U | L | 64-76 |
| NCAAB | 2022/02/26 19:00 | Loyola Maryland v American | L | 55-65 |
| NCAAB | 2022/02/24 00:00 | Loyola Maryland v Navy | L | 50-52 |