Stadium: Value City Arena
Home Manager: Chris Holtmann Away Manager: Barclay Radebaugh
| NCAAB | 2022/11/08 01:00 | Toccoa Falls v Charleston Southern | W | 52-83 |
| NCAAB | 2022/03/04 19:30 | Charleston Southern v USC Upstate | L | 62-72 |
| NCAAB | 2022/03/02 19:00 | Charleston Southern v UNC Asheville | W | 79-78 |
| NCAAB | 2022/02/26 21:00 | Charleston Southern v Winthrop | L | 86-92 |
| NCAAB | 2022/02/24 00:00 | Charleston Southern v Presbyterian | L | 48-68 |
| NCAAB | 2022/02/19 22:30 | USC Upstate v Charleston Southern | L | 78-73 |
| NCAAB | 2022/02/17 00:00 | UNC Asheville v Charleston Southern | L | 85-66 |
| NCAAB | 2022/02/12 19:00 | Charleston Southern v Gardner Webb | L | 65-82 |
| NCAAB | 2022/11/08 00:00 | Robert Morris v Ohio State | W | 53-91 |
| NCAAB | 2022/03/20 18:40 | Ohio State v Villanova | L | 61-71 |
| NCAAB | 2022/03/18 16:15 | Loyola Chicago v Ohio State | W | 41-54 |
| NCAAB | 2022/03/11 01:55 | Penn State v Ohio State | L | 71-68 |
| NCAAB | 2022/03/06 17:30 | Michigan v Ohio State | L | 75-69 |
| NCAAB | 2022/03/04 00:00 | Michigan State v Ohio State | W | 69-80 |
| NCAAB | 2022/03/02 00:00 | Nebraska v Ohio State | L | 78-70 |
| NCAAB | 2022/02/27 21:00 | Ohio State v Maryland | L | 60-75 |