[5] Clemson 73-83 Louisville [15] 2023-02-19 00:00
Stadium: KFC Yum! Center
Home Manager: Kenny Payne Away Manager: Brad Brownell
Head to Head
| NCAAB | 2023/01/12 02:00 | Louisville v Clemson | W | 70-83 |
| NCAAB | 2022/02/19 20:00 | Clemson v Louisville | L | 61-70 |
| NCAAB | 2021/01/28 02:00 | Louisville v Clemson | W | 50-54 |
| NCAAB | 2020/02/15 21:00 | Louisville v Clemson | W | 62-77 |
| NCAAB | 2020/01/25 19:00 | Clemson v Louisville | L | 62-80 |
| NCAAB | 2019/02/16 17:00 | Clemson v Louisville | L | 55-56 |
| NCAAB | 2018/01/06 17:00 | Louisville v Clemson | W | 69-74 |
| NCAAB | 2017/01/20 02:00 | Clemson v Louisville | L | 60-92 |
Home History
| NCAAB | 2023/02/16 00:00 | Florida State v Clemson | W | 54-94 |
| NCAAB | 2023/02/11 19:00 | Clemson v North Carolina | L | 71-91 |
| NCAAB | 2023/02/04 20:00 | Miami Florida v Clemson | L | 78-74 |
| NCAAB | 2023/02/01 00:00 | Clemson v Boston College | L | 54-62 |
| NCAAB | 2023/01/28 22:00 | Clemson v Florida State | W | 82-81 |
| NCAAB | 2023/01/25 02:00 | Georgia Tech v Clemson | W | 51-72 |
| NCAAB | 2023/01/21 23:00 | Virginia Tech v Clemson | W | 50-51 |
| NCAAB | 2023/01/18 02:00 | Clemson v Wake Forest | L | 77-87 |
Away History
| NCAAB | 2023/02/16 00:00 | Virginia v Louisville | L | 61-58 |
| NCAAB | 2023/02/12 00:00 | Louisville v Miami Florida | L | 85-93 |
| NCAAB | 2023/02/08 00:00 | Louisville v Pittsburgh | L | 57-91 |
| NCAAB | 2023/02/04 19:00 | Florida State v Louisville | L | 81-78 |
| NCAAB | 2023/02/02 00:00 | Georgia Tech v Louisville | W | 58-68 |
| NCAAB | 2023/01/28 17:00 | Louisville v Notre Dame | L | 62-76 |
| NCAAB | 2023/01/26 02:00 | Louisville v Boston College | L | 65-75 |
| NCAAB | 2023/01/19 00:00 | Pittsburgh v Louisville | L | 75-54 |