Stadium: Prather Coliseum
Home Manager: Corey Gipson Away Manager: Ryan Pedon
| NCAAB | 2022/11/11 01:00 | Illinois St v Eastern Illinois | W | 54-49 |
| NCAAB | 2022/11/08 01:00 | Western Illinois v Illinois St | L | 71-68 |
| NCAAB | 2022/03/04 18:00 | Illinois St v Northern Iowa | L | 65-78 |
| NCAAB | 2022/03/04 00:00 | Indiana State v Illinois St | W | 53-58 |
| NCAAB | 2022/02/26 21:00 | Indiana State v Illinois St | W | 66-86 |
| NCAAB | 2022/02/24 01:00 | Illinois St v Southern Illinois | L | 69-90 |
| NCAAB | 2022/02/22 01:00 | Loyola Chicago v Illinois St | L | 59-50 |
| NCAAB | 2022/02/19 19:00 | Illinois St v Bradley | L | 64-72 |
| NCAAB | 2022/11/10 18:00 | Ouachita Baptist v Northwestern State | W | 68-79 |
| NCAAB | 2022/11/08 02:00 | Northwestern State v Texas Tech | L | 49-73 |
| NCAAB | 2022/03/10 01:30 | McNeese State v Northwestern State | L | 80-67 |
| NCAAB | 2022/03/05 21:00 | SE Louisiana v Northwestern State | L | 85-80 |
| NCAAB | 2022/02/26 21:00 | New Orleans v Northwestern State | W | 77-87 |
| NCAAB | 2022/02/25 01:30 | Nicholls State v Northwestern State | L | 80-62 |
| NCAAB | 2022/02/19 23:00 | Northwestern State v Texas A&M Corpus | L | 76-83 |
| NCAAB | 2022/02/18 01:30 | Northwestern State v Incarnate Word | W | 88-64 |