Stadium: Sam M. Vadalabene Center
Home Manager: Brian Barone Away Manager: Ray Shovlain
| NCAAB | 2022/11/27 01:00 | SIU Edwardsville v Kansas City | W | 64-54 |
| NCAAB | 2022/11/20 18:30 | SIU Edwardsville v Longwood | W | 61-56 |
| NCAAB | 2022/11/20 00:30 | VMI v SIU Edwardsville | W | 67-93 |
| NCAAB | 2022/11/19 00:30 | SIU Edwardsville v Fairleigh Dickinson | W | 79-78 |
| NCAAB | 2022/11/16 01:00 | SIU Edwardsville v Missouri | L | 80-105 |
| NCAAB | 2022/11/12 18:00 | SIU Edwardsville v IPFW | L | 76-81 |
| NCAAB | 2022/11/08 01:00 | Harris Stowe v SIU Edwardsville | W | 57-85 |
| NCAAB | 2022/03/03 00:30 | SIU Edwardsville v Tennessee State | L | 62-77 |
| NCAAB | 2020/12/06 20:00 | Drake v St. Ambrose | L | 97-53 |
| NCAAB | 2020/12/05 00:00 | Northern Iowa v St. Ambrose | L | 98-53 |
| NCAAB | 2016/02/02 01:00 | Eastern Illinois v St. Ambrose | L | 101-59 |
| NCAAB | 2009/11/28 12:00 | Loyola Chicago v St. Ambrose | L | 81-42 |
| NCAAB | 2004/01/26 12:00 | Western Illinois v St. Ambrose | W | 65-80 |
| NCAAB | 2003/01/07 12:00 | Western Illinois v St. Ambrose | L | 110-83 |