Stadium: Minges Coliseum
Home Manager: Michael Schwartz Away Manager: Quinton Ferrell
| NCAAB | 2022/11/11 00:00 | Presbyterian v The Citadel | L | 58-70 |
| NCAAB | 2022/11/08 00:00 | Presbyterian v Piedmont International | W | 76-42 |
| NCAAB | 2022/03/03 01:30 | Presbyterian v Campbell | L | 72-75 |
| NCAAB | 2022/02/26 21:30 | Presbyterian v UNC Asheville | L | 96-98 |
| NCAAB | 2022/02/24 00:00 | Charleston Southern v Presbyterian | W | 48-68 |
| NCAAB | 2022/02/19 21:00 | Gardner Webb v Presbyterian | L | 76-68 |
| NCAAB | 2022/02/16 23:00 | Presbyterian v USC Upstate | L | 55-60 |
| NCAAB | 2022/02/12 21:30 | Presbyterian v Winthrop | L | 61-65 |
| NCAAB | 2022/11/09 00:00 | Mercer v East Carolina | W | 75-77 |
| NCAAB | 2022/03/10 18:00 | East Carolina v Cincinnati | L | 63-74 |
| NCAAB | 2022/03/05 20:00 | East Carolina v Wichita State | L | 62-70 |
| NCAAB | 2022/02/26 21:00 | Tulsa v East Carolina | W | 59-64 |
| NCAAB | 2022/02/24 00:00 | South Florida v East Carolina | W | 60-64 |
| NCAAB | 2022/02/20 19:00 | East Carolina v Central Florida | L | 66-69 |
| NCAAB | 2022/02/18 00:00 | East Carolina v South Florida | W | 65-57 |
| NCAAB | 2022/02/12 23:00 | SMU v East Carolina | L | 80-66 |