Stadium: The Buc Dome
Home Manager: Barclay Radebaugh Away Manager: Dave Dickerson
| NCAAB | 2022/03/04 19:30 | Charleston Southern v USC Upstate | W | 62-72 |
| NCAAB | 2022/02/19 22:30 | USC Upstate v Charleston Southern | W | 78-73 |
| NCAAB | 2022/01/22 21:00 | Charleston Southern v USC Upstate | W | 57-70 |
| NCAAB | 2020/02/10 23:00 | Charleston Southern v USC Upstate | W | 52-66 |
| NCAAB | 2020/01/03 00:30 | USC Upstate v Charleston Southern | L | 75-89 |
| NCAAB | 2019/03/06 00:00 | USC Upstate v Charleston Southern | L | 52-71 |
| NCAAB | 2019/02/22 00:30 | USC Upstate v Charleston Southern | L | 60-92 |
| NCAAB | 2019/02/02 21:30 | Charleston Southern v USC Upstate | L | 90-71 |
| NCAAB | 2022/12/29 22:00 | Winthrop v USC Upstate | W | 62-70 |
| NCAAB | 2022/12/21 00:00 | USC Upstate v Kennesaw State | L | 56-65 |
| NCAAB | 2022/12/14 01:30 | USC Upstate v Florida State | L | 63-80 |
| NCAAB | 2022/12/10 20:00 | South Carolina State v USC Upstate | W | 84-89 |
| NCAAB | 2022/12/03 22:30 | USC Upstate v Western Carolina | W | 79-64 |
| NCAAB | 2022/12/01 00:00 | USC Upstate v Columbia Intl | W | 93-59 |
| NCAAB | 2022/11/25 21:00 | USC Upstate v SC Gamecocks | L | 53-68 |
| NCAAB | 2022/11/22 02:00 | USC Upstate v Air Force | L | 56-83 |
| NCAAB | 2022/12/29 22:00 | Charleston Southern v Gardner Webb | L | 63-83 |
| NCAAB | 2022/12/22 20:00 | Kentucky Christian v Charleston Southern | W | 67-126 |
| NCAAB | 2022/12/17 21:00 | Charleston Southern v Jacksonville | L | 63-72 |
| NCAAB | 2022/12/15 01:00 | Charleston Southern v Tennessee State | W | 91-87 |
| NCAAB | 2022/12/06 00:00 | Kennesaw State v Charleston Southern | L | 76-65 |
| NCAAB | 2022/12/03 00:00 | Charleston Southern v South Florida | L | 59-79 |
| NCAAB | 2022/12/01 00:00 | The Citadel v Charleston Southern | L | 76-73 |
| NCAAB | 2022/11/26 01:00 | Charleston Southern v Virginia Tech | L | 64-69 |