Stadium: Francis S. Levien Gymnasium
Home Manager: Megan Griffith Away Manager: Kia Damon
| WNCAAB | 2022/11/30 23:00 | UMBC Women v Lafayette Women | W | 38-72 |
| WNCAAB | 2022/11/27 19:00 | Lafayette Women v Marist Women | L | 42-52 |
| WNCAAB | 2022/11/22 23:00 | La Salle Women v Lafayette Women | L | 71-54 |
| WNCAAB | 2022/11/19 19:00 | Lafayette Women v Siena Women | L | 55-63 |
| WNCAAB | 2022/11/17 00:00 | Lafayette Women v Cornell Women | L | 60-62 |
| WNCAAB | 2022/11/13 17:00 | East Tennessee State Women v Lafayette Women | L | 65-45 |
| WNCAAB | 2022/11/12 00:00 | Lafayette Women v NJIT Women | W | 62-58 |
| WNCAAB | 2022/11/07 16:00 | Lafayette Women v VA Commonwealth Women | L | 42-65 |
| WNCAAB | 2022/12/02 00:00 | Marist Women v Columbia Women | W | 54-103 |
| WNCAAB | 2022/11/27 19:00 | Columbia Women v Miami Florida Women | W | 78-71 |
| WNCAAB | 2022/11/25 18:00 | Arkansas Pine Bluff Women v Columbia Women | W | 57-95 |
| WNCAAB | 2022/11/20 17:00 | Columbia Women v Iowa State Women | L | 76-99 |
| WNCAAB | 2022/11/18 00:00 | Columbia Women v Seton Hall Women | W | 83-76 |
| WNCAAB | 2022/11/13 19:00 | Vanderbilt Women v Columbia Women | L | 74-63 |
| WNCAAB | 2022/11/11 00:00 | Columbia Women v Delaware Women | W | 64-56 |
| WNCAAB | 2022/11/08 01:00 | Columbia Women v Memphis Women | W | 77-69 |