Stadium: Chaifetz Arena
Home Manager: Rebecca Tillett Away Manager: Allison Guth
| WNCAAB | 2022/12/21 19:00 | Idaho State Women v Loyola Chicago Women | W | 44-56 |
| WNCAAB | 2022/12/20 17:00 | Elon Women v Loyola Chicago Women | W | 46-72 |
| WNCAAB | 2022/12/10 20:00 | Loyola Chicago Women v Marquette Women | L | 53-77 |
| WNCAAB | 2022/12/08 00:00 | DePaul Women v Loyola Chicago Women | L | 78-52 |
| WNCAAB | 2022/12/03 23:30 | Bradley Women v Loyola Chicago Women | W | 54-57 |
| WNCAAB | 2022/12/02 01:00 | Loyola Chicago Women v UIC Women | L | 36-45 |
| WNCAAB | 2022/11/29 00:00 | Loyola Chicago Women v Miami Ohio Women | L | 53-79 |
| WNCAAB | 2022/11/25 21:00 | Saint Francis PA Women v Loyola Chicago Women | W | 56-69 |
| WNCAAB | 2022/12/21 22:00 | Southern Illinois Women v St Louis Women | W | 54-82 |
| WNCAAB | 2022/12/17 20:00 | St Louis Women v Memphis Women | L | 71-83 |
| WNCAAB | 2022/12/09 01:00 | Wichita State Women v St Louis Women | L | 77-74 |
| WNCAAB | 2022/12/05 23:30 | St Louis Women v Ball State Women | L | 51-85 |
| WNCAAB | 2022/12/04 01:00 | Illinois State Women v St Louis Women | W | 65-75 |
| WNCAAB | 2022/12/01 01:00 | St Louis Women v Missouri Women | L | 52-82 |
| WNCAAB | 2022/11/27 16:00 | Air Force Women v St Louis Women | W | 58-77 |
| WNCAAB | 2022/11/26 16:00 | St Louis Women v Belmont Women | L | 68-78 |