Stadium: Virgin Islands Sport & Fitness Center
Home Manager: Kim English Away Manager: Jim Whitesell
| NCAAB | 2022/11/19 20:15 | Buffalo v Howard | L | 59-63 |
| NCAAB | 2022/11/18 18:00 | Buffalo v Drake | L | 72-80 |
| NCAAB | 2022/11/16 00:00 | Buffalo v Connecticut | L | 64-84 |
| NCAAB | 2022/11/12 18:00 | James Madison v Buffalo | L | 97-62 |
| NCAAB | 2022/11/08 00:00 | Colgate v Buffalo | W | 87-88 |
| NCAAB | 2022/03/10 18:30 | Buffalo v Akron | L | 68-70 |
| NCAAB | 2022/03/04 23:00 | Buffalo v Kent State | L | 65-70 |
| NCAAB | 2022/03/02 00:00 | Toledo v Buffalo | L | 92-76 |
| NCAAB | 2022/11/19 22:45 | Belmont v George Mason | L | 66-62 |
| NCAAB | 2022/11/19 01:00 | Boston College v George Mason | L | 71-56 |
| NCAAB | 2022/11/13 21:00 | American v George Mason | W | 56-73 |
| NCAAB | 2022/11/12 00:00 | Longwood v George Mason | W | 69-83 |
| NCAAB | 2022/11/08 01:00 | George Mason v Auburn | L | 52-70 |
| NCAAB | 2022/03/10 17:00 | George Mason v Fordham | L | 49-54 |
| NCAAB | 2022/03/05 21:00 | Massachusetts v George Mason | L | 83-80 |
| NCAAB | 2022/03/03 00:00 | George Mason v Davidson | L | 62-73 |