Stadium: Lantz Arena
Home Manager: Marty Simmons Away Manager: Michael Hunter
| NCAAB | 2022/11/17 00:00 | Eastern Illinois v Ohio State | L | 43-65 |
| NCAAB | 2022/11/13 19:00 | Eastern Illinois v Central Michigan | L | 60-76 |
| NCAAB | 2022/11/11 01:00 | Illinois St v Eastern Illinois | L | 54-49 |
| NCAAB | 2022/11/08 02:00 | Eastern Illinois v Illinois | L | 57-87 |
| NCAAB | 2022/02/26 21:30 | Austin Peay v Eastern Illinois | L | 64-52 |
| NCAAB | 2022/02/25 01:30 | Morehead State v Eastern Illinois | L | 82-46 |
| NCAAB | 2022/02/22 01:00 | Eastern Illinois v SIU Edwardsville | L | 52-66 |
| NCAAB | 2022/02/19 21:00 | Eastern Illinois v Tennessee State | L | 49-63 |