Head to Head
| Mexico Liga MX | 2022/08/15 00:05 | Tigres UANL v Santos Laguna | W | 2-0 |
| Mexico Liga MX | 2022/01/13 02:06 | Santos Laguna v Tigres UANL | D | 1-1 |
| Mexico Liga MX | 2021/11/29 00:00 | Tigres UANL v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2021/11/26 03:05 | Santos Laguna v Tigres UANL | L | 2-1 |
| Mexico Liga MX | 2021/08/08 02:00 | Tigres UANL v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2021/01/18 01:06 | Santos Laguna v Tigres UANL | L | 2-0 |
| Mexico Liga MX | 2020/09/13 00:00 | Tigres UANL v Santos Laguna | W | 2-0 |
| Mexico Liga MX | 2020/02/17 00:45 | Santos Laguna v Tigres UANL | L | 2-1 |
Home History
| Club Friendly List | 2022/12/23 03:00 | Tigres UANL v Chivas Guadalajara | L | 1-2 |
| Club Friendly List | 2022/12/18 03:00 | Tigres UANL v Atlas | W | 1-0 |
| Club Friendly List | 2022/12/14 03:00 | Tigres UANL v Mazatlan FC | D | 0-0 |
| Mexico Liga MX | 2022/10/17 02:06 | Pachuca v Tigres UANL | L | 2-1 |
| Mexico Liga MX | 2022/10/14 02:06 | Tigres UANL v Pachuca | W | 1-0 |
| Mexico Liga MX | 2022/10/09 00:00 | Tigres UANL v Necaxa | W | 2-0 |
| Mexico Liga MX | 2022/10/01 22:00 | Atletico San Luis v Tigres UANL | W | 0-3 |
| Club Friendly List | 2022/09/24 22:00 | FC Dallas v Tigres UANL | W | 0-3 |
Away History
| Club Friendly List | 2022/12/24 03:00 | Mazatlan FC v Santos Laguna | W | 2-3 |
| Club Friendly List | 2022/12/20 03:00 | Chivas Guadalajara v Santos Laguna | L | 4-0 |
| Club Friendly List | 2022/12/13 03:00 | Atlas v Santos Laguna | D | 0-0 |
| Mexico Liga MX | 2022/10/17 00:06 | Santos Laguna v Toluca | L | 1-2 |
| Mexico Liga MX | 2022/10/14 00:06 | Toluca v Santos Laguna | L | 4-3 |
| Mexico Liga MX | 2022/10/02 23:05 | Santos Laguna v Mazatlan FC | W | 3-0 |
| Mexico Liga MX | 2022/09/19 00:05 | Santos Laguna v Juarez FC | W | 2-0 |
| Mexico Liga MX | 2022/09/15 02:05 | Club America v Santos Laguna | D | 3-3 |