[6] Club America 3-1 Santos Laguna [16] 2016-10-30 02:00
Weather: Good Stadium: Azteca Pitch: Good Round: 15
Referee: Jorge Antonio Perez Duran Home Manager: Ricardo La Volpe Away Manager: Jose Manuel De la Torre
Head to Head
| CONCACAF Champions Cup | 2016/04/06 02:00 | Club America v Santos Laguna | W | 1-0 |
| CONCACAF Champions Cup | 2016/03/17 02:00 | Santos Laguna v Club America | D | 0-0 |
| Mexico Liga MX | 2016/02/06 23:00 | Club America v Santos Laguna | W | 2-0 |
| Mexico Liga MX | 2015/08/15 02:30 | Santos Laguna v Club America | W | 0-2 |
| Mexico Liga MX | 2015/03/14 23:00 | Club America v Santos Laguna | W | 1-0 |
| Mexico Liga MX | 2014/09/27 02:30 | Santos Laguna v Club America | W | 1-4 |
| Mexico Liga MX | 2014/05/04 02:00 | Santos Laguna v Club America | L | 3-1 |
| Mexico Liga MX | 2014/05/01 01:00 | Club America v Santos Laguna | W | 5-3 |
Home History
| Mexico Cup | 2016/10/27 02:00 | Club America v Chivas Guadalajara | L | 4-5 |
| Mexico Liga MX | 2016/10/23 00:00 | Queretaro v Club America | D | 1-1 |
| Mexico Cup | 2016/10/19 01:30 | Club America v Jaguares de Chiapas FC | W | 3-2 |
| Mexico Liga MX | 2016/10/16 02:00 | Club America v Tijuana | W | 1-0 |
| World Club Friendlies | 2016/10/09 01:00 | Club America v Unam Pumas | W | 1-0 |
| Mexico Liga MX | 2016/10/02 00:00 | Monterrey v Club America | D | 1-1 |
| Mexico Cup | 2016/09/29 02:00 | Club America v Veracruz | W | 1-0 |
| Mexico Liga MX | 2016/09/25 02:00 | Club America v Unam Pumas | W | 2-1 |
Away History
| Mexico Liga MX | 2016/10/23 23:00 | Santos Laguna v Atlas | D | 2-2 |
| Mexico Liga MX | 2016/10/16 00:06 | Pachuca v Santos Laguna | L | 3-0 |
| Mexico Liga MX | 2016/10/01 22:00 | Queretaro v Santos Laguna | D | 1-1 |
| Mexico Liga MX | 2016/09/25 23:00 | Santos Laguna v Tijuana | L | 1-2 |
| Mexico Liga MX | 2016/09/22 02:30 | Monterrey v Santos Laguna | L | 5-2 |
| Mexico Liga MX | 2016/09/18 23:00 | Santos Laguna v Unam Pumas | W | 3-1 |
| Mexico Cup | 2016/09/14 02:30 | Santos Laguna v Veracruz | D | 1-1 |
| Mexico Liga MX | 2016/09/11 02:00 | Necaxa v Santos Laguna | L | 2-1 |