| Uruguay Reserve League | 2017/12/14 19:30 | Nacional de Montevideo Reserves v Defensor Sporting Reserves | D | 2-2 |
| Uruguay Reserve League | 2017/12/11 13:00 | Juventud De Las Piedras Reserves v Defensor Sporting Reserves | W | 0-2 |
| Uruguay Reserve League | 2017/12/03 17:30 | Defensor Sporting Reserves v Atletico Fenix Reserves | L | 1-2 |
| Uruguay Reserve League | 2017/11/29 13:00 | Defensor Sporting Reserves v Montevideo Wanderers Reserves | W | 2-0 |
| Uruguay Reserve League | 2017/11/20 13:00 | Boston River Reserves v Defensor Sporting Reserves | W | 0-2 |
| Uruguay Reserve League | 2017/11/16 20:00 | Defensor Sporting Reserves v Liverpool Montevideo Reserves | W | 2-1 |
| Uruguay Reserve League | 2017/11/13 13:00 | El Tanque Sisley Reserves v Defensor Sporting Reserves | W | 0-1 |
| Uruguay Reserve League | 2017/11/07 14:00 | CA Cerro Reserves v Defensor Sporting Reserves | L | 2-0 |