[16] BUF Sabres 3-4 FLA Panthers [9] 2018-04-07 23:00
Stadium: Amerant Bank Arena Round: 1
Home Manager: Bob Boughner Away Manager: Phil Housley
Head to Head
| NHL | 2018/03/03 00:30 | BUF Sabres v FLA Panthers | L | 1-4 |
| NHL | 2018/02/02 00:00 | FLA Panthers v BUF Sabres | L | 4-2 |
| NHL | 2017/11/11 00:00 | FLA Panthers v BUF Sabres | L | 4-1 |
| NHL | 2017/04/08 23:00 | BUF Sabres v FLA Panthers | L | 0-3 |
| NHL | 2017/03/27 23:00 | FLA Panthers v BUF Sabres | W | 2-4 |
| NHL | 2016/12/21 00:30 | BUF Sabres v FLA Panthers | L | 3-4 |
| NHL | 2016/10/29 16:53 | FLA Panthers v BUF Sabres | W | 0-3 |
Home History
| NHL | 2018/04/06 23:30 | BUF Sabres v TB Lightning | L | 5-7 |
| NHL | 2018/04/04 23:30 | OTT Senators v BUF Sabres | L | 4-2 |
| NHL | 2018/04/02 23:00 | BUF Sabres v TOR Maple Leafs | L | 2-5 |
| NHL | 2018/04/01 00:00 | BUF Sabres v NAS Predators | W | 7-4 |
| NHL | 2018/03/29 23:00 | DET Red Wings v BUF Sabres | L | 6-3 |
| NHL | 2018/03/26 23:00 | BUF Sabres v TOR Maple Leafs | W | 3-2 |
| NHL | 2018/03/24 23:00 | BUF Sabres v NY Rangers | L | 1-5 |
| NHL | 2018/03/23 23:00 | MON Canadiens v BUF Sabres | L | 3-0 |
Away History
| NHL | 2018/04/05 23:30 | BOS Bruins v FLA Panthers | W | 2-3 |
| NHL | 2018/04/03 23:30 | NAS Predators v FLA Panthers | W | 1-2 |
| NHL | 2018/04/02 23:30 | CAR Hurricanes v FLA Panthers | W | 2-3 |
| NHL | 2018/03/31 17:00 | FLA Panthers v BOS Bruins | L | 1-5 |
| NHL | 2018/03/29 23:30 | FLA Panthers v OTT Senators | L | 2-3 |
| NHL | 2018/03/28 23:30 | FLA Panthers v TOR Maple Leafs | L | 3-4 |
| NHL | 2018/03/26 23:00 | FLA Panthers v NY Islanders | W | 3-0 |
| NHL | 2018/03/24 23:00 | ARZ Coyotes v FLA Panthers | W | 2-4 |