Stadium: Banterra Center Round: 1
Home Manager: Barry Hinson Away Manager: Porter Moser
| NCAAB | 2018/01/18 01:00 | Southern Illinois v Loyola Chicago | W | 65-79 |
| NCAAB | 2017/03/03 20:00 | Loyola Chicago v Southern Illinois | L | 50-55 |
| NCAAB | 2017/02/26 01:00 | Loyola Chicago v Southern Illinois | L | 70-72 |
| NCAAB | 2017/02/04 19:00 | Southern Illinois v Loyola Chicago | L | 67-61 |
| NCAAB | 2016/02/07 01:00 | Southern Illinois v Loyola Chicago | W | 59-73 |
| NCAAB | 2015/12/31 01:00 | Loyola Chicago v Southern Illinois | L | 62-72 |
| NCAAB | 2015/02/12 01:00 | Loyola Chicago v Southern Illinois | W | 66-62 |
| NCAAB | 2015/01/18 23:05 | Southern Illinois v Loyola Chicago | L | 59-52 |
| NCAAB | 2018/02/18 21:00 | Loyola Chicago v Evansville | W | 76-66 |
| NCAAB | 2018/02/15 01:00 | Valparaiso v Loyola Chicago | W | 71-80 |
| NCAAB | 2018/02/10 19:00 | Loyola Chicago v Indiana State | W | 75-71 |
| NCAAB | 2018/02/08 01:00 | Drake v Loyola Chicago | W | 57-72 |
| NCAAB | 2018/02/03 19:00 | Missouri State v Loyola Chicago | W | 75-97 |
| NCAAB | 2018/02/01 01:00 | Loyola Chicago v Bradley | L | 67-69 |
| NCAAB | 2018/01/28 21:00 | Northern Iowa v Loyola Chicago | W | 47-70 |
| NCAAB | 2018/01/25 01:00 | Loyola Chicago v Drake | W | 80-57 |
| NCAAB | 2018/02/17 19:00 | Southern Illinois v Indiana State | W | 76-72 |
| NCAAB | 2018/02/15 01:00 | Missouri State v Southern Illinois | W | 80-81 |
| NCAAB | 2018/02/11 21:00 | Bradley v Southern Illinois | W | 57-74 |
| NCAAB | 2018/02/09 02:00 | Southern Illinois v Illinois St | L | 68-76 |
| NCAAB | 2018/02/04 01:00 | Valparaiso v Southern Illinois | W | 59-65 |
| NCAAB | 2018/01/31 01:00 | Southern Illinois v Drake | W | 78-67 |
| NCAAB | 2018/01/27 23:00 | Southern Illinois v Missouri State | W | 79-77 |
| NCAAB | 2018/01/25 01:00 | Indiana State v Southern Illinois | W | 77-82 |