| Colombia Regional League | 2023/03/06 14:16 | Lula FC v Medellin City FC | L | 2-1 |
| Colombia Regional League | 2022/10/24 15:00 | Deportivo Alexis Garcia v Medellin City FC | W | 0-3 |
| Colombia Regional League | 2022/10/18 13:00 | Medellin City FC v Envigado FC Reserves | W | 1-0 |
| Colombia Regional League | 2022/10/04 17:00 | Medellin City FC v Politecnico J.I.C. | W | 3-0 |
| Colombia Regional League | 2022/09/21 15:00 | Molino Viejo v Medellin City FC | L | 3-0 |
| Colombia Regional League | 2022/09/07 17:00 | Sol de Oriente v Medellin City FC | L | 2-1 |
| Colombia Regional League | 2022/08/30 15:00 | Medellin City FC v FC Leones Reserves | W | 4-0 |
| Colombia Regional League | 2022/08/15 15:13 | Real Santuario v Medellin City FC | L | 4-0 |
| Colombia Regional League | 2023/03/23 17:00 | Talento y Vida v Atletico Nacional Medellin Reserves | L | 2-5 |
| Colombia Regional League | 2022/10/31 15:00 | Talento y Vida v Envigado FC Reserves | L | 0-1 |
| Colombia Regional League | 2022/10/01 17:13 | Molino Viejo v Talento y Vida | W | 0-1 |
| Colombia Regional League | 2022/09/26 17:11 | Talento y Vida v Total Soccer FC | W | 2-0 |
| Colombia Regional League | 2022/09/17 19:00 | Deportivo Alexis Garcia v Talento y Vida | L | 2-0 |
| Colombia Regional League | 2022/09/05 15:34 | FC Leones Reserves v Talento y Vida | W | 2-3 |
| Colombia Regional League | 2022/07/28 16:14 | Independiente Sabaneta v Talento y Vida | W | 0-1 |
| Colombia Regional League | 2022/07/10 17:36 | E.D.P IND. Medellin v Talento y Vida | D | 1-1 |