[5] SD Padres 4-1 HOU Astros [1] 2018-04-07 00:10
Stadium: Minute Maid Park Round: 1
Home Manager: A.J. Hinch Away Manager: Darren Balsley
Head to Head
| MLB Exhibition | 2016/03/27 19:00 | SD Padres v HOU Astros | W | 21-6 |
| MLB Exhibition | 2016/03/27 01:00 | SD Padres v HOU Astros | L | 1-11 |
| MLB | 2015/04/29 19:40 | SD Padres v HOU Astros | L | 2-7 |
Home History
| MLB | 2018/04/05 19:40 | COL Rockies v SD Padres | L | 3-1 |
| MLB | 2018/04/05 02:10 | COL Rockies v SD Padres | L | 5-2 |
| MLB | 2018/04/04 02:10 | COL Rockies v SD Padres | W | 4-8 |
| MLB | 2018/04/03 02:10 | COL Rockies v SD Padres | L | 7-4 |
| MLB | 2018/04/01 00:40 | MIL Brewers v SD Padres | L | 7-3 |
| MLB | 2018/03/31 02:10 | MIL Brewers v SD Padres | L | 8-6 |
| MLB | 2018/03/29 20:10 | MIL Brewers v SD Padres | L | 2-1 |
| MLB Spring Training | 2018/03/25 19:10 | SEA Mariners v SD Padres | L | 11-7 |
Away History
| MLB | 2018/04/04 18:10 | BAL Orioles v HOU Astros | W | 2-3 |
| MLB | 2018/04/04 00:10 | BAL Orioles v HOU Astros | W | 6-10 |
| MLB | 2018/04/02 23:10 | BAL Orioles v HOU Astros | W | 1-6 |
| MLB | 2018/04/01 19:05 | HOU Astros v TEX Rangers | W | 8-2 |
| MLB | 2018/03/31 20:05 | HOU Astros v TEX Rangers | W | 9-3 |
| MLB | 2018/03/31 00:05 | HOU Astros v TEX Rangers | L | 1-5 |
| MLB | 2018/03/29 19:35 | HOU Astros v TEX Rangers | W | 4-1 |
| MLB Spring Training | 2018/03/27 18:10 | MIL Brewers v HOU Astros | W | 1-8 |