Head to Head
| Mexico U20 League | 2022/09/22 14:00 | Toluca U20 v Santos Laguna U20 | L | 1-0 |
| Mexico U20 League | 2022/01/16 15:00 | Toluca U20 v Santos Laguna U20 | L | 4-2 |
| Mexico U20 League | 2021/10/24 16:00 | Santos Laguna U20 v Toluca U20 | W | 3-0 |
| Mexico U20 League | 2021/04/18 16:00 | Santos Laguna U20 v Toluca U20 | D | 2-2 |
| Mexico U20 League | 2020/09/20 14:00 | Toluca U20 v Santos Laguna U20 | L | 1-0 |
| Mexico U20 League | 2019/11/24 15:00 | Toluca U20 v Santos Laguna U20 | D | 2-2 |
| Mexico U20 League | 2019/05/12 16:15 | Santos Laguna U20 v Toluca U20 | W | 2-0 |
| Mexico U20 League | 2019/05/09 14:00 | Toluca U20 v Santos Laguna U20 | L | 2-1 |
Home History
| Mexico U20 League | 2023/04/16 15:00 | Monterrey U20 v Santos Laguna U20 | L | 2-1 |
| Mexico U20 League | 2023/04/09 17:00 | Santos Laguna U20 v Pachuca U20 | L | 1-3 |
| Mexico U20 League | 2023/03/31 15:00 | Necaxa U20 v Santos Laguna U20 | W | 0-2 |
| Mexico U20 League | 2023/03/19 15:00 | Leon U20 v Santos Laguna U20 | W | 1-3 |
| Mexico U20 League | 2023/03/12 17:00 | Santos Laguna U20 v Tijuana U20 | L | 1-3 |
| Mexico U20 League | 2023/03/04 15:00 | Chivas Guadalajara U20 v Santos Laguna U20 | L | 1-0 |
| Mexico U20 League | 2023/02/26 17:00 | Santos Laguna U20 v Puebla U20 | W | 4-3 |
| Mexico U20 League | 2023/02/18 15:00 | Atletico San Luis U20 v Santos Laguna U20 | W | 0-1 |
Away History
| Mexico U20 League | 2023/04/16 15:00 | Unam Pumas U20 v Toluca U20 | W | 1-2 |
| Mexico U20 League | 2023/04/07 15:00 | Puebla U20 v Toluca U20 | W | 0-1 |
| Mexico U20 League | 2023/04/02 14:00 | Toluca U20 v Tigres U20 | W | 2-1 |
| Mexico U20 League | 2023/03/17 22:45 | Tijuana U20 v Toluca U20 | D | 2-2 |
| Mexico U20 League | 2023/03/12 15:00 | Toluca U20 v Mazatlan FC U20 | L | 0-1 |
| Mexico U20 League | 2023/03/05 15:00 | Queretaro U20 v Toluca U20 | W | 0-4 |
| Mexico U20 League | 2023/02/26 15:00 | Toluca U20 v Atletico San Luis U20 | W | 3-0 |
| Mexico U20 League | 2023/02/19 18:00 | Pachuca U20 v Toluca U20 | W | 1-2 |