Head to Head
| NCAAF | 2015/11/08 00:00 | Oklahoma v Iowa State | W | 52-16 |
| NCAAF | 2014/11/01 16:00 | Iowa State v Oklahoma | W | 14-59 |
| NCAAF | 2012/11/03 12:00 | Iowa State v Oklahoma | W | 20-35 |
| NCAAF | 2011/11/26 12:00 | Oklahoma v Iowa State | W | 26-6 |
| NCAAF | 2010/10/16 12:00 | Oklahoma v Iowa State | W | 52-0 |
| NCAAF | 2007/10/20 12:00 | Iowa State v Oklahoma | W | 7-17 |
| NCAAF | 2006/10/14 12:00 | Oklahoma v Iowa State | W | 34-9 |
| NCAAF | 2003/10/04 12:00 | Iowa State v Oklahoma | W | 7-53 |
Home History
| NCAAF | 2016/10/29 23:00 | Kansas v Oklahoma | W | 3-56 |
| NCAAF | 2016/10/23 00:00 | Oklahoma v Texas Tech | W | 66-59 |
| NCAAF | 2016/10/15 16:00 | Kansas State v Oklahoma | W | 17-38 |
| NCAAF | 2016/10/08 16:00 | Oklahoma v Texas | W | 45-40 |
| NCAAF | 2016/10/01 21:00 | Oklahoma v TCU | W | 52-46 |
| NCAAF | 2016/09/18 01:00 | Ohio State v Oklahoma | L | 45-24 |
| NCAAF | 2016/09/10 23:00 | Oklahoma v UL Monroe | W | 59-17 |
| NCAAF | 2016/09/03 16:00 | Oklahoma v Houston | L | 23-33 |
Away History
| NCAAF | 2016/10/29 16:00 | Kansas State v Iowa State | L | 31-26 |
| NCAAF | 2016/10/15 23:00 | Iowa State v Texas | L | 6-27 |
| NCAAF | 2016/10/08 19:30 | Iowa State v Oklahoma State | L | 31-38 |
| NCAAF | 2016/10/01 16:00 | Baylor v Iowa State | L | 45-42 |
| NCAAF | 2016/09/24 16:00 | San Jose State v Iowa State | W | 10-44 |
| NCAAF | 2016/09/17 16:00 | Iowa State v TCU | L | 20-41 |
| NCAAF | 2016/09/10 23:30 | Iowa v Iowa State | L | 42-3 |
| NCAAF | 2016/09/04 00:00 | Iowa State v Northern Iowa | L | 20-25 |