[13] Southern Mississippi 34-31 UL Lafayette [15] 2023-11-10 00:30
Stadium: Cajun Field Round: 1
Home Manager: Michael Desormeaux Away Manager: Will Hall
Head to Head
| NCAAF | 2022/10/27 23:30 | Lafayette v Southern Mississippi | W | 24-39 |
| NCAAF | 2016/12/18 02:00 | Southern Mississippi v Lafayette | W | 28-21 |
| NCAAF | 2008/08/30 12:00 | Southern Mississippi v Lafayette | W | 51-21 |
| NCAAF | 2003/11/01 12:00 | Southern Mississippi v Lafayette | W | 48-3 |
| NCAAF | 2001/09/22 12:00 | Lafayette v Southern Mississippi | W | 10-35 |
Home History
| NCAAF | 2023/11/04 20:00 | UL Monroe v Southern Mississippi | W | 7-24 |
| NCAAF | 2023/10/28 19:30 | Southern Mississippi v Appalachian St | L | 38-48 |
| NCAAF | 2023/10/17 23:30 | Southern Mississippi v South Alabama | L | 3-55 |
| NCAAF | 2023/10/07 23:00 | Old Dominion v Southern Mississippi | L | 17-13 |
| NCAAF | 2023/09/30 23:00 | Texas State v Southern Mississippi | L | 50-36 |
| NCAAF | 2023/09/23 23:00 | Southern Mississippi v Arkansas State | L | 37-44 |
| NCAAF | 2023/09/16 20:00 | Tulane v Southern Mississippi | L | 21-3 |
| NCAAF | 2023/09/10 00:30 | Southern Mississippi v Florida State | L | 13-66 |
Away History
| NCAAF | 2023/11/04 19:00 | Lafayette v Arkansas State | L | 17-37 |
| NCAAF | 2023/11/04 16:30 | Colgate v Lafayette | L | 37-34 |
| NCAAF | 2023/10/28 21:00 | Lafayette v South Alabama | W | 33-20 |
| NCAAF | 2023/10/28 16:30 | Lafayette v Georgetown | W | 35-25 |
| NCAAF | 2023/10/22 00:00 | Georgia State v Lafayette | L | 20-17 |
| NCAAF | 2023/10/21 17:00 | Lafayette v Holy Cross | W | 38-35 |
| NCAAF | 2023/10/07 19:30 | Texas State v Lafayette | W | 30-34 |
| NCAAF | 2023/10/07 17:00 | Lafayette v Princeton | W | 12-9 |