[5] Alexander Zverev 7-6,4-6,4-6 John Isner [17] 2018-04-01 17:00
Stadium: Stadium Round: 29 Ground: Hardcourt outdoor
Head to Head
| ATP Rome | 2017/05/20 13:00 | Alexander Zverev v John Isner | 6-4,6-7,6-1 |
| ATP Miami | 2017/03/27 20:40 | John Isner v Alexander Zverev | 7-6,6-7,6-7 |
| ATP Shanghai | 2016/10/10 07:10 | Alexander Zverev v John Isner | 6-4,6-2 |
Home History
| ATP Miami | 2018/03/30 23:00 | Pablo Carreno Busta v Alexander Zverev | 6-7,2-6 |
| ATP Miami | 2018/03/30 00:25 | Alexander Zverev v Borna Coric | 6-4,6-4 |
| ATP Miami | 2018/03/28 01:30 | Alexander Zverev v Nick Kyrgios | 6-4,6-4 |
| ATP Miami | 2018/03/26 23:30 | Alexander Zverev v David Ferrer | 2-6,6-2,6-4 |
| ATP Miami | 2018/03/24 15:00 | Alexander Zverev v Daniil Medvedev | 6-4,1-6,7-6 |
| ATP Indian Wells | 2018/03/12 03:45 | Joao Sousa v Alexander Zverev | 7-5,5-7,6-4 |
| ATP Acapulco | 2018/03/03 04:55 | Juan Martin Del Potro v Alexander Zverev | 6-4,6-2 |
| ATP Acapulco | 2018/03/01 23:30 | Ryan Harrison v Alexander Zverev | 4-6,1-6 |
Away History
| ATP Miami | 2018/03/30 17:00 | Juan Martin Del Potro v John Isner | 1-6,6-7 |
| ATP Miami | 2018/03/28 19:00 | Hyeon Chung v John Isner | 1-6,4-6 |
| ATP Miami | 2018/03/27 15:00 | John Isner v Marin Cilic | 7-6,6-3 |
| ATP Miami | 2018/03/25 21:25 | John Isner v Mikhail Youzhny | 6-4,6-3 |
| ATP Miami | 2018/03/23 21:50 | John Isner v Jiri Vesely | 7-6,1-6,6-3 |
| ATP Indian Wells | 2018/03/11 18:00 | John Isner v Gael Monfils | 7-6,6-7,5-7 |
| ATP Acapulco | 2018/02/27 01:00 | John Isner v Ryan Harrison | 3-6,6-7 |
| ATP Delray Beach | 2018/02/21 17:40 | Peter Gojowczyk v John Isner | 7-6,6-7,7-6 |